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Animal Sciences

Utah State University

Poisonous Plant Research (PPR)

Aversive substance

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Isolation Of The Toxic Principle Of Senecio Latifolius By Means Of The Sensory Receptors Of Sheep, Leendert D. Snyman Dec 2023

Isolation Of The Toxic Principle Of Senecio Latifolius By Means Of The Sensory Receptors Of Sheep, Leendert D. Snyman

Poisonous Plant Research (PPR)

The aversive substance of Senecio latifolius was isolated by means of the sensory receptors of sheep averted to S. latifolius. Chemical fractions refused due to the presence of the aversive substance sensed by the sheep were fractionated until a purified substance had been isolated. Nuclear magnetic resonance (NMR) analysis of the purified substance showed it to be sceleratine nitrogen oxide, the toxic principle of S. latifolius.