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Life Sciences Commons

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Animal Sciences

Utah State University

Animal, Dairy, and Veterinary Science Student Research

Skeletal muscle growth

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Full-Text Articles in Life Sciences

Understanding The Influence Of Trenbolone Acetate And Polyamines On Proliferation Of Bovine Satellite Cells, Caleb C. Reichhardt, Amir Ahmadpour, Rachael G. Christensen, Nikole E. Ineck, Gordon Murdoch, Kara Thornton-Kurth Mar 2020

Understanding The Influence Of Trenbolone Acetate And Polyamines On Proliferation Of Bovine Satellite Cells, Caleb C. Reichhardt, Amir Ahmadpour, Rachael G. Christensen, Nikole E. Ineck, Gordon Murdoch, Kara Thornton-Kurth

Animal, Dairy, and Veterinary Science Student Research

Approximately 90% of beef cattle on feed in the United States receive at least one anabolic implant, which results in increased growth, efficiency, and economic return to producers. However, the complete molecular mechanism through which anabolic implants function to improve skeletal muscle growth remains unknown. This study had 2 objectives: (1) determine the effect of polyamines and their precursors on proliferation rate in bovine satellite cells (BSC); and (2) understand whether trenbolone acetate (TBA), a testosterone analog, has an impact on the polyamine biosynthetic pathway. To address these, BSC were isolated from 3 finished steers and cultured. Once cultures reached …