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Plague Persistence In Western Europe: A Hypothesis, Ann G. Carmichael Jan 2014

Plague Persistence In Western Europe: A Hypothesis, Ann G. Carmichael

The Medieval Globe

Historical sources documenting recurrent plagues of the “Second Pandemic” usually focus on urban epidemic mortality. Instead, plague persists in remote, rural hinterlands: areas less visible in the written sources of late medieval Europe. Plague spreads as fleas move from relatively resistant rodents, which serve as “maintenance hosts,” to an array of more susceptible rural mammals, now called “amplifying hosts.” Using sources relevant to plague in thinly populated Central and Western Alpine regions, this paper postulates that Alpine Europe could have been a region of plague persistence via its population of wild rodents, particularly the Alpine marmot.


Heterogeneous Immunological Landscapes And Medieval Plague: An Invitation To A New Dialogue Between Historians And Immunologists, Fabian Crespo, Matt B. Lawrenz Jan 2014

Heterogeneous Immunological Landscapes And Medieval Plague: An Invitation To A New Dialogue Between Historians And Immunologists, Fabian Crespo, Matt B. Lawrenz

The Medieval Globe

Efforts to understand the differential mortality caused by plague must account for many factors, including human immune responses. In this essay we are particularly interested in those people who were exposed to the Yersinia pestis pathogen during the Black Death, but who had differing fates—survival or death—that could depend on which individuals (once infected) were able to mount an appropriate immune response as a result of biological, environmental, and social factors. The proposed model suggests that historians of the medieval world could make a significant contribution to the study of human health, and especially the role of human immunology in …