Engineering Commons^™

Machine Learning-Based Peripheral Artery Disease Identification Using Laboratory-Based Gait Data, Ali Al-Ramini, Mahdi Hassan, Farahnaz Fallahtafti, Mohammad Ali Takallou, Hafizur Rahman, Basheer Qolomany, Iraklis I. Pipinos, Fadi M. Alsaleem, Sara A. Myers

Department of Mechanical and Materials Engineering: Faculty Publications

Peripheral artery disease (PAD) manifests from atherosclerosis, which limits blood flow to the legs and causes changes in muscle structure and function, and in gait performance. PAD is underdiagnosed, which delays treatment and worsens clinical outcomes. To overcome this challenge, the purpose of this study is to develop machine learning (ML) models that distinguish individuals with and without PAD. This is the first step to using ML to identify those with PAD risk early. We built ML models based on previously acquired overground walking biomechanics data from patients with PAD and healthy controls. Gait signatures were characterized using ankle, knee, …

Machine Learning-Based Peripheral Artery Disease Identification Using Laboratory-Based Gait Data, Ali Al-Ramini, Mahdi Hassan, Farahnaz Fallahtafti, Mohammad Ali Takallou, Basheer Qolomany, Iraklis I. Pipinos, Fadi Alsaleem, Sara A. Myers

Department of Mechanical and Materials Engineering: Faculty Publications

Peripheral artery disease (PAD) manifests from atherosclerosis, which limits blood flow to the legs and causes changes in muscle structure and function, and in gait performance. PAD is underdiagnosed, which delays treatment and worsens clinical outcomes. To overcome this challenge, the purpose of this study is to develop machine learning (ML) models that distinguish individuals with and without PAD. This is the first step to using ML to identify those with PAD risk early. We built ML models based on previously acquired overground walking biomechanics data from patients with PAD and healthy controls. Gait signatures were characterized using ankle, knee, …

On Geometric Design Rules And In-Process Build Quality Monitoring Of Thin-Wall Features Made Using Laser Powder Bed Fusion Additive Manufacturing Process, Aniruddha Gaikwad

Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research

The goal of this thesis is to quantify the link between the design features (geometry), in-process signatures, and build quality of parts made using the laser powder bed fusion (LPBF) additive manufacturing (AM) process. This knowledge is the foundational basis for proposing design rules in AM, as well as for detecting the impending build failures using in-process sensor data.

As a step towards this goal, the objectives of this work are two-fold:

1) Quantify the effect of the geometry and orientation on the build quality of thin-wall features. To explain further, the geometry related factor is the ratio of the …

Deep Learning Segmentation Of Coronary Calcified Plaque From Intravascular Optical Coherence Tomography (Ivoct) Images With Application To Finite Element Modeling Of Stent Deployment, Yazan Gharaibeh, Pengfei Dong, David Prabhu, Chaitanya Kolluru, Juhwan Lee, Vlad Zimin, Hozhabr Mozafari, Hiram Bizzera, Linxia Gu, David Wilson

Department of Mechanical and Materials Engineering: Faculty Publications

Because coronary artery calcified plaques can hinder or eliminate stent deployment, interventional cardiologists need a better way to plan interventions, which might include one of the many methods for calcification modification (e.g., atherectomy). We are imaging calcifications with intravascular optical coherence tomography (IVOCT), which is the lone intravascular imaging technique with the ability to image the extent of a calcification, and using results to build vessel-specific finite element models for stent deployment. We applied methods to a large set of image data (>45 lesions and > 2,600 image frames) of calcified plaques, manually segmented by experts into calcified, lumen and …