Engineering Commons^™

Nonuniform Sampling-Based Breast Cancer Classification, Santiago Posso

Theses and Dissertations--Electrical and Computer Engineering

The emergence of deep learning models and their success in visual object recognition have fueled the medical imaging community's interest in integrating these algorithms to improve medical diagnosis. However, natural images, which have been the main focus of deep learning models and mammograms, exhibit fundamental differences. First, breast tissue abnormalities are often smaller than salient objects in natural images. Second, breast images have significantly higher resolutions but are generally heavily downsampled to fit these images to deep learning models. Models that handle high-resolution mammograms require many exams and complex architectures. Additionally, spatially resizing mammograms leads to losing discriminative details essential …

Using Case-Level Context To Classify Cancer Pathology Reports, Shang Gao, Mohammed Alawad, Noah Schaefferkoetter, Lynne Penberthy, Xiao-Cheng Wu, Eric B. Durbin, Linda Coyle, Arvind Ramanathan, Georgia Tourassi

Kentucky Cancer Registry Faculty Publications

Individual electronic health records (EHRs) and clinical reports are often part of a larger sequence-for example, a single patient may generate multiple reports over the trajectory of a disease. In applications such as cancer pathology reports, it is necessary not only to extract information from individual reports, but also to capture aggregate information regarding the entire cancer case based off case-level context from all reports in the sequence. In this paper, we introduce a simple modular add-on for capturing case-level context that is designed to be compatible with most existing deep learning architectures for text classification on individual reports. We …

Image-Based Roadway Assessment Using Convolutional Neural Networks, Weilian Song

Theses and Dissertations--Computer Science

Road crashes are one of the main causes of death in the United States. To reduce the number of accidents, roadway assessment programs take a proactive approach, collecting data and identifying high-risk roads before crashes occur. However, the cost of data acquisition and manual annotation has restricted the effect of these programs. In this thesis, we propose methods to automate the task of roadway safety assessment using deep learning. Specifically, we trained convolutional neural networks on publicly available roadway images to predict safety-related metrics: the star rating score and free-flow speed. Inference speeds for our methods are mere milliseconds, enabling …

Novel Applications Of Machine Learning In Bioinformatics, Yi Zhang

Theses and Dissertations--Computer Science

Technological advances in next-generation sequencing and biomedical imaging have led to a rapid increase in biomedical data dimension and acquisition rate, which is challenging the conventional data analysis strategies. Modern machine learning techniques promise to leverage large data sets for finding hidden patterns within them, and for making accurate predictions. This dissertation aims to design novel machine learning-based models to transform biomedical big data into valuable biological insights. The research presented in this dissertation focuses on three bioinformatics domains: splice junction classification, gene regulatory network reconstruction, and lesion detection in mammograms.

A critical step in defining gene structures and mRNA …

Automated Tree-Level Forest Quantification Using Airborne Lidar, Hamid Hamraz

Theses and Dissertations--Computer Science

Traditional forest management relies on a small field sample and interpretation of aerial photography that not only are costly to execute but also yield inaccurate estimates of the entire forest in question. Airborne light detection and ranging (LiDAR) is a remote sensing technology that records point clouds representing the 3D structure of a forest canopy and the terrain underneath. We present a method for segmenting individual trees from the LiDAR point clouds without making prior assumptions about tree crown shapes and sizes. We then present a method that vertically stratifies the point cloud to an overstory and multiple understory tree …

3d Body Tracking Using Deep Learning, Qingguo Xu

Theses and Dissertations--Computer Science

This thesis introduces a 3D body tracking system based on neutral networks and 3D geometry, which can robustly estimate body poses and accurate body joints. This system takes RGB-D data as input. Body poses and joints are firstly extracted from color image using deep learning approach. The estimated joints and skeletons are further translated to 3D space by using camera calibration information. This system is running at the rate of 3 4 frames per second. It can be used to any RGB-D sensors, such as Kinect, Intel RealSense [14] or any customized system with color depth calibrated. Comparing to the …