Engineering Commons^™

Deep Learning For Quantitative Susceptibility Mapping Reconstruction, Juan Liu

Dissertations (1934 -)

Quantitative susceptibility mapping (QSM) is a magnetic resonance imaging (MRI) technique that estimates tissue magnetic susceptibility from Larmor frequency offset measurements. The generation of QSM requires solving ill-posed background field removal (BFR) and field-to-source inversion problems. Incorrect BFR often introduces erroneous local field outputs and subsequently affects susceptibility quantification accuracy. Inaccurate field-to-source inversion often causes large susceptibility estimation errors that appear as streaking artifacts in the QSM, especially in massive hemorrhagic regions. Because current QSM techniques struggle to generate reliable QSM, the clinical translation of QSM is greatly hindered. Recently, deep learning (DL) has achieved state-of-the-art performance in many computer …