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Full-Text Articles in Engineering
Blast Shock-Wave Characterization In Experimental Shock Tubes, Sudeepto Kahali
Blast Shock-Wave Characterization In Experimental Shock Tubes, Sudeepto Kahali
Dissertations
Blast-induced traumatic brain injuries have affected U.S. soldiers deployed for extended periods in the gulf and Afghanistan wars. To identify the biomechanical and biochemical mechanisms of injury, critical in the identification of diagnostic and therapeutic tools, compressed gas-driven shock tubes are used by investigators to study shockwave-animal specimen interactions and its biological consequences. However, shock tubes are designed and operated in a variety of geometry with a range of process parameters, and the quality of shock wave characteristics relevant to field conditions and therefore the study of blast-induced traumatic brain injuries suffered by soldiers is affected by those conditions. Lab-to-lab …
Biomechanical Loading Changes Between Species In Mild Blast-Induced Traumatic Brain Injury, Jose Juan Rodriguez
Biomechanical Loading Changes Between Species In Mild Blast-Induced Traumatic Brain Injury, Jose Juan Rodriguez
Dissertations
Blast-induced traumatic brain injury (bTBI) has become one of the leading injury modalities in military personnel and is considered a signature injury in veterans returning from conflicts in the Middle East. One of the main concerns in studying bTBI is translating animal experiments to clinical applications that can service veterans. Significant advances have been made using animal models in relating external shock waves to emerging neuropathophysiological and behavioral outcomes. However, it is unknown if these results are applicable to humans; and if so, can an interspecies transfer function be developed based on size, shape, and material response. This work aims …
Identification Of Neurobiological Mechanisms Associated With Attention Deficits In Adults Post Traumatic Brain Injury, Ziyan Wu
Dissertations
Traumatic Brain Injury (TBI) is one of the major public health concerns with approximately 70 million new cases occurring worldwide per year. It is often caused by a forceful bump, blow, or jolt to the head, resulting in brain tissue damage and normal brain functions disruption. All grades of TBI, ranging from mild to severe, can cause wide-ranging and long-term effects on affected individuals, resulting in physical impairments, and neurocognitive consequences that permanently affect their abilities to perform daily activities. Attention deficits are the most common persisting neurocognitive consequences following TBI, which significantly contribute to poor academic and social functioning, …