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Engineering Commons

Open Access. Powered by Scholars. Published by Universities.®

2019

Coatings

Selected Works

Articles 1 - 2 of 2

Full-Text Articles in Engineering

Application-Specific Oxide-Based And Metal-Dielectric Thin Film Materials Prepared By Rf Magnetron Sputtering Preprints201908.0184.V1.Pdf, Mohammad Nur-E-Alam, Wade Lonsdale, Mikhail Vasiliev, Kamal Alameh Aug 2019

Application-Specific Oxide-Based And Metal-Dielectric Thin Film Materials Prepared By Rf Magnetron Sputtering Preprints201908.0184.V1.Pdf, Mohammad Nur-E-Alam, Wade Lonsdale, Mikhail Vasiliev, Kamal Alameh

Mikhail Vasiliev

We report on the development of several different thin-film functional material systems prepared by RF magnetron sputtering at Edith Cowan University nanofabrication labs. We conduct research on the design, prototyping, and practical fabrication of high-performance magneto-optic (MO) materials, oxide based sensor components, and heat regulation coatings for advanced construction and solar windows.


Collagen-Mimetic Hydrogels Promote Human Endothelial Cell Adhesion, Migration And Phenotypic Maturation, Dany J. Munoz Pinto, V. R. Guiza-Arguello, S. M. Becerra-Bayona, J. Erndt-Marino, S. Samavedi, S. Malmut, B. Russell, M. Höök, M. S. Hahn Apr 2019

Collagen-Mimetic Hydrogels Promote Human Endothelial Cell Adhesion, Migration And Phenotypic Maturation, Dany J. Munoz Pinto, V. R. Guiza-Arguello, S. M. Becerra-Bayona, J. Erndt-Marino, S. Samavedi, S. Malmut, B. Russell, M. Höök, M. S. Hahn

Dany J. Munoz Pinto

This work evaluates the response of human aortic endothelial cells (HAECs) to thromboresistant collagen-mimetic hydrogel coatings toward improving the biocompatibility of existing "off-the-shelf" small-caliber vascular grafts. Specifically, bioactive hydrogels-previously shown to support α1/α2 integrin-mediated cell adhesion but to resist platelet activation-were fabricated by combining poly(ethylene glycol) (PEG) with a 120 kDa, triple-helical collagen-mimetic protein (Scl2-2) containing the GFPGER adhesion sequence. Analysis of HAECs seeded onto the resulting PEG-Scl2-2 hydrogels demonstrated that HAEC adhesion increased with increasing Scl2-2 concentration, while HAEC migration rate decreased over this same concentration range. In addition, evaluation of HAEC phenotype at confluence indicated significant differences in …