Open Access. Powered by Scholars. Published by Universities.®

Engineering Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 2 of 2

Full-Text Articles in Engineering

Development Of A Comsol Microdialysis Model, Towards Creation Of Microdialysis On A Chip With Improved Geometries And Recovery, Patrick Pysz Dec 2019

Development Of A Comsol Microdialysis Model, Towards Creation Of Microdialysis On A Chip With Improved Geometries And Recovery, Patrick Pysz

Graduate Theses and Dissertations

Microdialysis (µD) sampling is a diffusion-limited sampling method that has been widely used in different biomedical fields for greater than 35 years. Device calibration for in vivo studies is difficult for current non-steady state analytes of interest correlated with both inflammatory response and microbial signaling molecules (QS); which exist in low ng/mL to pg/mL with molecular weights over a wide range of 170 Da to 70 kDa. The primary performance metric, relative recovery (RR), relating the collected sample to the extracellular space concentration varies from 10% to 60% per analyte even under controlled bench-top conditions. Innovations in microdialysis device design …


Computational And Experimental Development Of 2d Anisotropic Photonic Crystal Metamaterials, James A. Ethridge Mar 2019

Computational And Experimental Development Of 2d Anisotropic Photonic Crystal Metamaterials, James A. Ethridge

Theses and Dissertations

The future of optical devices involves manipulation of nanoscale structure in order to achieve full control over the properties of the device. In fields as diverse as directed energy, remote sensing, optical communications and optical computing, these devices promise to greatly improve performance and efficiency. To advance this further, novel samples that incorporate both photonic crystal (PhC) structure and metamaterial properties, known as PhC metamaterials, are proposed. These PhC metamaterials allow for complete control over the directionality of the light-matter interaction to serve in these new applications. To develop this technology, first, metamaterials with no PhC structure are fabricated using …