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Theses/Dissertations

1975

Amino Acids

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A Kinetic Study Of Lysine And Lysine Derivatives, Stephen Joseph Stanley May 1975

A Kinetic Study Of Lysine And Lysine Derivatives, Stephen Joseph Stanley

Theses

The kinetics of the reaction of iodoacetamide with lysine, polylysine, N-α-Acetyl lysine, and N-ε-Acetyl lysine, have been studied. The investigation was done at 23° C ± 123° C, as a function of pH, and concentration. In all cases it was noted that the rate of reaction increased as the pH increased. The rate data was analyzed in order to obtain the second order rate constants. In addition, the effects of the reactive site's environment on the rate was demonstrated.