Engineering Commons^™

Investigating The Effects Of Alcohol Consumption On Manual And Automated Driving: A Systematic Review, Miaomiao Dong, Yuni Lee, Jackie Cha, Gaojian Huang

Mineta Transportation Institute

There are direct correlations between drunk driving and car-related injuries, disabilities, and death. Autonomous vehicles (AVs) may provide useful driver support systems to prevent or reduce road accidents. However, AVs are not yet fully automated and require human drivers to take over the vehicle at times. Therefore, understanding how alcohol affects driving performance in both manual and automated driving is important because manual drives may offer insights into the takeover process in AVs. A systematic review of 53 articles from eight databases was conducted. Findings were categorized based on the human information processing model, which can be extended to the …

Increased Liver Stiffness Promotes Hepatitis B Progression By Impairing Innate Immunity In Ccl4-Induced Fibrotic Hbv+ Transgenic Mice, Grace Bybee, Youra Moeun, Weimin Wang, Kusum K. Kharbanda, Larisa Y. Poluektova, Srivatsan Kidambi, Natalia A. Osna, Murali Ganesan

Department of Chemical and Biomolecular Engineering: Faculty Publications

Background: Hepatitis B virus (HBV) infection develops as an acute or chronic liver disease, which progresses from steatosis, hepatitis, and fibrosis to end-stage liver diseases such as cirrhosis and hepatocellular carcinoma (HCC). An increased stromal stiffness accompanies fibrosis in chronic liver diseases and is considered a strong predictor for disease progression. The goal of this study was to establish the mechanisms by which enhanced liver stiffness regulates HBV infectivity in the fibrotic liver tissue. Methods: For in vitro studies, HBV-transfected HepG2.2.15 cells were cultured on polydimethylsiloxane gels coated by polyelectrolyte multilayer films of 2 kPa (soft) or 24 kPa (stiff) …

Cellular Bioenergetics: Experimental Evidence For Alcohol-Induced Adaptations, Liz Simon, Patricia E. Molina

School of Medicine Faculty Publications

At-risk alcohol use is associated with multisystemic effects and end-organ injury, and significantly contributes to global health burden. Several alcohol-mediated mechanisms have been identified, with bioenergetic maladaptation gaining credence as an underlying pathophysiological mechanism contributing to cellular injury. This evidence-based review focuses on the current knowledge of alcohol-induced bioenergetic adaptations in metabolically active tissues: liver, cardiac and skeletal muscle, pancreas, and brain. Alcohol metabolism itself significantly interferes with bioenergetic pathways in tissues, particularly the liver. Alcohol decreases states of respiration in the electron transport chain, and activity and expression of respiratory complexes, with a net effect to decrease ATP content. …

Multivariate Analysis For The Quantification Of Transdermal Volatile Organic Compounds In Humans By Proton Exchange Membrane Fuel Cell System, Ahmed Hasnain Jalal

FIU Electronic Theses and Dissertations

In this research, a proton exchange membrane fuel cell (PEMFC) sensor was investigated for specific detection of volatile organic compounds (VOCs) for point-of-care (POC) diagnosis of the physiological conditions of humans. A PEMFC is an electrochemical transducer that converts chemical energy into electrical energy. A Redox reaction takes place at its electrodes whereas the volatile biomolecules (e.g. ethanol) are oxidized at the anode and ambient oxygen is reduced at the cathode. The compounds which were the focus of this investigation were ethanol (C₂H₅OH) and isoflurane (C₃H₂ClF₅O), but theoretically, the sensor …

Precision Of Emr Data: The Case For A Drug And Alcohol Service, Siyu Qian, Esther Munyisia, Ping Yu, David M. Hailey, David Reid

Faculty of Engineering and Information Sciences - Papers: Part B

Error-laden data can negatively affect clinical and operational decision making, research findings and funding allocation. This study examined the number and types of data errors in an electronic medical record (EMR) system in a Drug and Alcohol service. Specifically, errors in service data were examined. 9,379 errors were identified from ten error reports generated between March 2015 and May 2016, three months after the implementation of the EMR system. These errors were grouped into four types: mismatched data fields (60.5%), duplicate medical record error (3.2%), date/time error (8.8%) and blank field error (27.4%). The errors can be prevented by adding …

In Vitro Mechanical Fatigue Behavior Of Poly-Ɛ-Caprolactone Macroporous Scaffolds For Cartilage Tissue Engineering: Influence Of Pore Filling By A Poly(Vinyl Alcohol) Gel, J A. Panadero, L Vikingsson, J L. Gomez Ribelles, Senentxu Lanceros-Méndez, Vitor Sencadas

Faculty of Engineering and Information Sciences - Papers: Part A

Polymeric scaffolds used in regenerative therapies are implanted in the damaged tissue and submitted to repeated loading cycles. In the case of articular cartilage engineering, an implanted scaffold is typically subjected to long-term dynamic compression. The evolution of the mechanical properties of the scaffold during bioresorption has been deeply studied in the past, but the possibility of failure due to mechanical fatigue has not been properly addressed. Nevertheless, the macroporous scaffold is susceptible to failure after repeated loading-unloading cycles. In this work fatigue studies of polycaprolactone scaffolds were carried by subjecting the scaffold to repeated compression cycles in conditions simulating …

Low-Energy Electron Scattering From Α-Tetrahydrofurfuryl Alcohol, Luca Chiari, Darryl Jones, Penny Thoi, Michael J. Brungei, Gustavo Garcia, Francisco Blanco

Faculty of Engineering and Information Sciences - Papers: Part A

We report on differential cross section results for low-energy electron collisions with the biologically relevant species a-tetrahydrofurfuryl alcohol. Electron-impact excitation measurements of the electronic states of a-tetrahydrofurfuryl alcohol were carried out at incident energies between 15-50 eV and for scattering angles in the range 20-90 degrees. Elastic differential cross section have also been calculated within the Independent Atom Model and using the Screening Corrected Additivity Rule approach at selected energies between 1-1000 eV.

Analysis Of Traffic Accident Data In Kentucky (1990- 1994), Kenneth R. Agent, Jerry G. Pigman

Kentucky Transportation Center Research Report

This report includes an analysis of traffic accident data in Kentucky for the years of 1990-1994. A primary objective of this study was to determine average accident statistics for Kentucky highways. Average and critical numbers and rates of accidents were calculated for various types of highways in rural and urban areas. These data can be used in Kentucky's procedure to identify locations that have abnormal rates or numbers of accidents.

Another objective of this study was to provide data which can be used in the preparation of the problem identification portion of Kentucky's Annual Highway Safety Plan. County and city …

Analysis Of Traffic Accident Data In Kentucky (1989-1993), Kenneth R. Agent, Jerry G. Pigman

Kentucky Transportation Center Research Report

This report includes an analysis of traffic accident data in Kentucky for the years of 1989-1993. A primary objective of this study was to determine average accident statistics for Kentucky highways. Average and critical numbers and rates of accidents were calculated for various types of highways in rural and urban areas. These data can be used in Kentucky's procedure to identify locations that have abnormal rates or numbers of accidents.

Another objective of this study was to provide data which can be used in the preparation of the problem identification portion of Kentucky's Annual Highway Safety Plan. County and city …

Analysis Of Alcohol And Speed Related Traffic Accidents In Fayette County, Kenneth R. Agent

Kentucky Transportation Center Research Report

One objective of this study was to update the statistics related to alcohol-related accidents and arrests In Fayette County. The second objective was to include an analysis of speed-related accidents and citations.

The number of alcohol-related accidents in Fayette County has decreased over the past several years. The number of speed-related accidents has remained relatively constant Differences between the characteristics of all accidents and alcohol and speed-related accidents were noted. For example, there were higher percentages of alcohol and speed-related accidents involving a fixed object. Differences in driver characteristics, such as the high percentage of drivers in the 16 to …

Analysis Of Traffic Accident Data In Kentucky (1988-1992), Kenneth R. Agent, Jerry G. Pigman

Kentucky Transportation Center Research Report

This report includes an analysis of traffic accident data in Kentucky tor the years of 1988-1992. A primary objective of this study was to determine average accident statistics tor Kentucky highways. Average and critical numbers and rates at accidents were calculated for various types of highways in rural and urban areas. These data can be used in Kentucky's procedure to identify locations that have abnormal rates or numbers of accidents.

Another objective of this study was to provide data which can be used in the preparation of the problem identification portion of Kentucky's Annual Highway Safety Plan. County and city …

Analysis Of Traffic Accident Data In Kentucky (1987-1991), Kenneth R. Agent, Jerry G. Pigman

Kentucky Transportation Center Research Report

This report includes an analysis of traffic accident data in Kentucky tor the years of 1987-1991. A primary objective of this study was to determine average accident statistics for Kentucky highways. Average and critical number and rates of accidents were calculated for various types of highways in rural and urban areas. These data can be used in Kentucky's procedure to identify locations that have abnormal rates or numbers of accidents.

Another objective of this study was to provide data which can be used in the preparation of the problem identification portion of Kentucky's Annual Highway Safety Plan. County and city …

Analysis Of Traffic Accident Data In Kentucky (1986-1990), Kenneth R. Agent, Jerry G. Pigman

Kentucky Transportation Center Research Report

This report includes an analysis of traffic accident data in Kentucky for the years of 1986-1990. A primary objective of this study was to determine average accident statistics for Kentucky highways. Average and critical number and rates of accidents were calculated for various types of highways in rural and urban areas. These data can be used in Kentucky's procedure to identify locations that have abnormal rates or numbers of accidents.

Another objective of this study was to provide data which can be used in the preparation of the problem identification portion of Kentucky's Annual Highway Safety Plan. County and city …

Analysis Of Traffic Accident Data In Kentucky (1985-1989), Kenneth R. Agent, Jerry G. Pigman

Kentucky Transportation Center Research Report

This report includes an analysis of traffic accident data in Kentucky for the years of 1985 through 1989. A primary objective of this study was to determine average accident statistics for Kentucky highways. Average and critical number and rates of accidents were calculated for various types of highways in rural and urban areas. These data can be used in Kentucky's procedure to identify locations that have abnormal rates or numbers of accidents.

Another objective of this study was to provide data which can be used in the preparation of the problem identification portion of Kentucky's Annual Highway Safety Plan. County …

Analysis Of Accident Data In Kentucky (1984-1988), Kenneth R. Agent, Jerry G. Pigman

Kentucky Transportation Center Research Report

Kentucky has a systematic procedure to identify locations that have abnormal rates or numbers of accidents. This procedure utilizes average accident rates and numbers. A primary objective of this study was to determine average accident statistics in Kentucky. An annual safety program for Kentucky, which includes the identification, programming, budgeting, and evaluation of safety projects, is prepared each year. The data presented in this report may be included as the problem identification portion of Kentucky's Annual Highway Safety Plan.

Average and critical accident rates were calculated by highway type for rural and urban highways. A summary of results and recommendations …

Analysis Of Accident Data In Kentucky (1983-1987), Kenneth R. Agent, Jerry G. Pigman

Kentucky Transportation Center Research Report

Kentucky has a systematic procedure to identify locations that have abnormal rates or numbers of accidents. This procedure utilizes average accident rates and numbers. A primary objective of this study was to determine average accident statistics in Kentucky. An annual safety program for Kentucky, which includes the identification, programming, budgeting, and evaluation of safety projects, is prepared each year. The data presented in this report may be included as the problem identification portion of Kentucky's Annual Highway Safety Plan.

Average and critical accident rates were calculated by highway type for rural and urban highways. A summary of results and recommendations …

Impact Evaluation Of The Louisville-Shively-Jefferson County Traffic Alcohol Programs, Jerry G. Pigman, Kenneth R. Agent, Patricia L. Hardyman, Knowlton W. Johnson, Richard Mccleary

Kentucky Transportation Center Research Report

This report is an evaluation of alcohol enforcement programs conducted by the Louisville, Jefferson County, and Shively police agencies in the Louisville metropolitan area. The following four types of data were collected in order to evaluate the traffic alcohol programs; accident data, arrest and adjudication data, cost-effectiveness, and public opinion data.

Results from the before-and-after comparisons and time-series analysis show alcohol-related accidents decreased significantly during the study period, There was a 34.4 percent reduction in alcohol-related accidents during hours of special enforcement and a 30.4 percent reduction during all hours of the day. Time-series analysis of accident data showed a …

Analysis Of Accident Data In Kentucky (1982-1986), Kenneth R. Agent, Jerry G. Pigman

Kentucky Transportation Center Research Report

Kentucky has a systematic procedure to identify locations that have abnormal rates or numbers of accidents. This procedure utilizes average accident rates and numbers. A primary objective of this study was to determine average accident statistics in Kentucky. An annual safety program for Kentucky, which includes the identification, programming, budgeting, and evaluation of safety projects, is prepared each year. The data presented in this report may be included as the problem identification portion of Kentucky's Annual Highway Safety Plan.

Average and critical accident rates were calculated by highway type for rural and urban highways. A summary of results and recommendations …

Impact Evaluation Of The Lexington-Fayette County Traffic Alcohol Program (1982-1986), Jerry G. Pigman, Kenneth R. Agent

Kentucky Transportation Center Research Report

This report is a final evaluation of four years of increased police enforcement to reduce alcohol-related accidents in Lexington-Fayette County, Kentucky. Three types of data were collected as a means of evaluating the Traffic Alcohol Program; accident data, arrest and adjudication data, and cost-effectiveness data.

Results from before-and-after comparisons and time-series analysis show alcohol-related accidents decreased significantly during the study period. When comparing two years before with four years during the increased enforcement, the reduction in alcohol-related accidents during hours of increased enforcement was 37.3 percent using standard before and after analysis and 36.4 percent using time-series analysis. For all …

Impact Evaluation Of The Traffic Alcohol Program In Lexington, Kentucky, Jerry G. Pigman, Kenneth R. Agent

Kentucky Transportation Center Research Report

This report is an evaluation of increased police enforcement to reduce alcohol-related accidents in Lexington-Fayette County, Kentucky. Three types of data were coIlected as a means of evaluating the Traffic Alcohol Program; accident data, arrest and adjudication data, and cost-effectiveness data.

Results from before-and-after comparisons and time-series analysis show alcohol related accidents decreased significantly during the study period. When comparing two years before with three years during the increased enforcement, the percent reduction in alcohol-related accidents was 28.1 percent using standard before and after analysis and 29.1 percent using time-series analysis. During the same time period, alcohol related fatal or …

Problem Identification For Highway Safety Plan, Jerry G. Pigman, Kenneth R. Agent

Kentucky Transportation Center Research Report

An annual highway safety program is proposed each year for the State of Kentucky in order to comply with Section 402, Title 23 of the United States Code. This program includes the identification, programming, budgeting, and evaluation of safety projects. This report is the sixth in a series of annual reports which have been prepared as the problem identification portion of Kentucky's Annual Highway Safety Plan.

In the past, the approach to problem identification has been to identify problem areas in the 18 highway safety program areas (standards). While the search for problems in each of these standard areas will …

Impact Evaluation Of Traffic Alcohol Programs: Selected Locations In Kentucky, Jerry G. Pigman, Kenneth R. Agent

Kentucky Transportation Center Research Report

This report is an evaluation of increased police enforcement to reduce alcohol-related accidents at selected locations in Kentucky. Evaluations were performed for the following programs: 1) Lexington-Fayette County, including only Urban Police enforcement; 2) McCracken County, including Kentucky State Police, Sheriff's Office and Paducah Police enforcement; and 3) Warren County, including both Kentucky State Police and Bowling Green Police enforcement. Duration of enforcement and level of enforcement varied among the programs.

Four types of data were collected as a means of evaluating Traffic Alcohol Programs at the locations selected for study; accident data, arrest and adjudication data, cost-effectiveness data, and …

Alcohol Impact Evaluation (Interim Report), Jerry G. Pigman, Kenneth R. Agent

Kentucky Transportation Center Research Report

This report is an evaluation of increased police enforcement to reduce alcohol related accidents in Lexington-Fayette County, Kentucky. Three types of information were collected for the analysis; accident data, arrest and adjudication data, and personal opinion data obtained by means of a questionnaire survey. Accident data were collected for two years before the Traffic Alcohol Program (TAP) and one year during the program. A 25 percent sample of arrest and adjudication data was collected one year before and one year during TAP. The questionnaire was sent to 2,500 registered vehicle owners.

Results from before-and-after comparisons and time-series analysis show alchol …

Problem Identification For Highway Safety Plan (Fy 1984), Jerry G. Pigman, Kenneth R. Agent, Tom Creasey

Kentucky Transportation Center Research Report

An annual highway safety program is proposed each year for the State of Kentucky in order to comply with Section 402, Title 23 of the United States Code. This program includes the identification, programming, budgeting, and evaluation of safety projects. This report is the fifth in a series of annual reports which have been included as the problem identification portion of Kentucky's Annual Highway Safety Plan.

In the past, the approach to problem identification has been to identify problem areas in the 18 highway safety program areas (standards). While the search for problems in each of these standard areas will …

Problem Identification For Highway Safety Plan (Fy 1983), Kenneth R. Agent, Joseph D. Crabtree, Jerry G. Pigman

Kentucky Transportation Center Research Report

An annual highway safety program is proposed each year for the State of Kentucky in order to comply with Section 402, Title 23 of the United States code. This program includes the identification, programming, budgeting, and evaluation of safety projects. This report is the fourth in a series of annual reports which have been included as the problem identification portion of Kentucky's Annual Highway Safety Plan.

The approach used in this study involved identifying problem areas related to the 18 highway safety program standards with added emphasis placed on selected areas. This resulted in the analysis of 19 problem identification …

Energy In Agriculture: Energy Resource Series For Youth And Adult Energy Programs: 12. Alcohol, George M. Turner

Agricultural Engineering Energy Series

Today we often hear discussed the potential energy content and ability of alcohol to lessen our dependence on gasoline as a motor fuel. The alcohol in question is ethyl alcohol, a colorless, volatile, flammable liquid that is derived from growing plants, or the parts of growing plants, that are relatively high in carbohydrate content.