Open Access. Powered by Scholars. Published by Universities.®

Engineering Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 4 of 4

Full-Text Articles in Engineering

Fkrr-Mvsf: A Fuzzy Kernel Ridge Regression Model For Identifying Dna-Binding Proteins By Multi-View Sequence Features Via Chou's Five-Step Rule, Yi Zou, Yijie Ding, Jijun Tang, Fei Guo, Li Peng Sep 2019

Fkrr-Mvsf: A Fuzzy Kernel Ridge Regression Model For Identifying Dna-Binding Proteins By Multi-View Sequence Features Via Chou's Five-Step Rule, Yi Zou, Yijie Ding, Jijun Tang, Fei Guo, Li Peng

Faculty Publications

DNA-binding proteins play an important role in cell metabolism. In biological laboratories, the detection methods of DNA-binding proteins includes yeast one-hybrid methods, bacterial singles and X-ray crystallography methods and others, but these methods involve a lot of labor, material and time. In recent years, many computation-based approachs have been proposed to detect DNA-binding proteins. In this paper, a machine learning-based method, which is called the Fuzzy Kernel Ridge Regression model based on Multi-View Sequence Features (FKRR-MVSF), is proposed to identifying DNA-binding proteins. First of all, multi-view sequence features are extracted from protein sequences. Next, a Multiple Kernel Learning (MKL) algorithm …


Fkrr-Mvsf: A Fuzzy Kernel Ridge Regression Model For Identifying Dna-Binding Proteins By Multi-View Sequence Features Via Chou's Five-Step Rule, Yi Zou, Yije Ding, Jijun Tang, Fei Guo, Li Peng Sep 2019

Fkrr-Mvsf: A Fuzzy Kernel Ridge Regression Model For Identifying Dna-Binding Proteins By Multi-View Sequence Features Via Chou's Five-Step Rule, Yi Zou, Yije Ding, Jijun Tang, Fei Guo, Li Peng

Faculty Publications

DNA-binding proteins play an important role in cell metabolism. In biological laboratories, the detection methods of DNA-binding proteins includes yeast one-hybrid methods, bacterial singles and X-ray crystallography methods and others, but these methods involve a lot of labor, material and time. In recent years, many computation-based approachs have been proposed to detect DNA-binding proteins. In this paper, a machine learning-based method, which is called the Fuzzy Kernel Ridge Regression model based on Multi-View Sequence Features (FKRR-MVSF), is proposed to identifying DNA-binding proteins. First of all, multi-view sequence features are extracted from protein sequences. Next, a Multiple Kernel Learning (MKL) algorithm …


Low-Rank Sparse Subspace For Spectral Clustering, Xiaofeng Zhu, Shichao Zhang, Yonggang Li, Jilian Zhang, Lifeng Yang, Yue Fang Aug 2019

Low-Rank Sparse Subspace For Spectral Clustering, Xiaofeng Zhu, Shichao Zhang, Yonggang Li, Jilian Zhang, Lifeng Yang, Yue Fang

Research Collection School Of Computing and Information Systems

The current two-step clustering methods separately learn the similarity matrix and conduct k means clustering. Moreover, the similarity matrix is learnt from the original data, which usually contain noise. As a consequence, these clustering methods cannot achieve good clustering results. To address these issues, this paper proposes a new graph clustering methods (namely Low-rank Sparse Subspace clustering (LSS)) to simultaneously learn the similarity matrix and conduct the clustering from the low-dimensional feature space of the original data. Specifically, the proposed LSS integrates the learning of similarity matrix of the original feature space, the learning of similarity matrix of the low-dimensional …


Transfer Learning Approach To Multiclass Classification Of Child Facial Expressions, Megan A. Witherow, Manar D. Samad, Khan M. Iftekharuddin Jan 2019

Transfer Learning Approach To Multiclass Classification Of Child Facial Expressions, Megan A. Witherow, Manar D. Samad, Khan M. Iftekharuddin

Electrical & Computer Engineering Faculty Publications

The classification of facial expression has been extensively studied using adult facial images which are not appropriate ground truths for classifying facial expressions in children. The state-of-the-art deep learning approaches have been successful in the classification of facial expressions in adults. A deep learning model may be better able to learn the subtle but important features underlying child facial expressions and improve upon the performance of traditional machine learning and feature extraction methods. However, unlike adult data, only a limited number of ground truth images exist for training and validating models for child facial expression classification and there is a …