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Bioresorbable Composite Stents For Enhanced Response Of Vascular Smooth Muscle Cells, Hozhabr Mozafari
Bioresorbable Composite Stents For Enhanced Response Of Vascular Smooth Muscle Cells, Hozhabr Mozafari
Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research
Formation of arterial plaque and stenosis is one of the main cardiovascular disease risk factors. Stenting is a popular approach to increase the inner diameter of the artery and provide an acceptable lumen gain. This is achieved by applying internal pressure to the arterial wall. Despite the desirable outcomes of this procedure, there are complexities and challenges that are being discussed among scholars in this area. Restenosis is one of these complications, in which smooth muscles cell start proliferation and remodeling in response of induced mechanical stresses. Another important issue is the placement of the stent and possible migration due …
Gas Embolic Factors In Cardiovascular Health, Eric L. Cutler
Gas Embolic Factors In Cardiovascular Health, Eric L. Cutler
Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research
Gas emboli are a clinical issue often encountered in the space exploration, marine construction, and medical fields. Individuals involved with these disciplines will often have asympomatic gas emboli circulating throughout their bodies on a regular basis. A study into the impact of chronic asymptomatic gas emboli on the risk of atherosclerosis in humans is thus presented. This research utilized a custom built cardiovascular flow simulator and accompanying data acquisition system to experimentally determine the influence of gas emboli under varied circumstances on the mean wall shear stress of a tube in-vitro. A directly inverse relationship between gas embolus presence in …