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Single-Use Technologies: Bridging Polymer Science to Biotechnology Applications
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An Investigational Study On The Impact Of An Incopatible Filtration Of Benzyl Alcohol Using A Polyethersulfone Membrane, Michael Difiore
An Investigational Study On The Impact Of An Incopatible Filtration Of Benzyl Alcohol Using A Polyethersulfone Membrane, Michael Difiore
Single-Use Technologies: Bridging Polymer Science to Biotechnology Applications
Chemical compatibility of a process stream with a disposable component is a critical element of determining the suitability of the single-use system. Chemical compatibility is often a collection of data on the physical interactions of a disposable with a solution, including but not limited to filter integrity, membrane swelling, and hardware deformations. Compatibility conditions recommended by the disposable manufacturer such as solvent concentration, temperature, and contact time should be compared to actual process use conditions. An incompatible filtration operation can impact the integrity of the filter, in addition to introducing material-derived impurities to a process stream that may not be …