Engineering Commons^™

Better Models For High-Stakes Tasks, Jacob Ryan Epifano

Theses and Dissertations

The intersection of machine learning and healthcare has the potential to transform medical diagnosis, treatment, and research. Machine learning models can analyze vast amounts of medical data and identify patterns that may be too complex for human analysis. However, one of the major challenges in this field is building trust between users and the model. Due to things like high false alarm rate and the black box nature of machine learning models, patients and medical professionals need to understand how the model arrives at its recommendations. In this work, we present several methods that aim to improve machine learning models …

Supplier Performance Scorecard Utilization In The Medical Device Manufacturing Healthcare Supply Chain, Justin Cardisco

Theses and Dissertations

The medical device manufacturing industry has a deficiency in determining how to improve supplier performance for the components and systems they purchase. Many complex medical devices require components from superb suppliers. But how does a medical device manufacturer (MDM) impartially assess supplier performance to know which suppliers to continuing with (or even boost purchase volumes) and which suppliers they should exit? This study describes which supplier-specific metrics are most important to medical device manufacturers (MDMs) so they can utilize this supplier performance scorecard backed by real-world inputs. This research will focus on five categories to measure MDM supplier performance (Quality, …

A Systematic Approach To High Blood Pressure Risk Analysis And Healthcare Cost Reduction In Young Adults [Metodología Sistemática Para El Análisis De Riesgo Y Reducción De Costos De Servicios Médicos De Hipertensión En Adultos Jóvenes], Francisco Rafael Torres Diaz

Theses and Dissertations

The purpose of this research is to utilize publicly available data to estimate the current rate of occurrence of undiagnosed High Blood Pressure (HBP) in young adults (18 to 24 years old) and the out-of-pocket healthcare expenses associated with complications of HBP, to provide feasible alternatives to mitigate the effects on a region's economy. This has been done by building a Risk Factor Simulation Model that utilizes known HBP risk factors’ correlation to HBP, insurance coverage data, and rate of diagnosis to formulate the average Risk Factor Value for a region, which through an Annual Expected Cost Function estimates the …

Identification Of The Mechanisms Through Which Botanicals Attenuate Pathogenesis Of Human Diseases, Esraah Alharris

Theses and Dissertations

Plant products have been used for a long time in treatment of diseases. In fact, more than half of approved medicines are derived from plants or other natural products. Even though the synthetic drugs are effective in treating many human diseases, there is no cure against several clinical disorders. Moreover, a significant number of diseases can be prevented thereby causing less burden on societal healthcare costs as well as promoting healthy lifestyles. Thus, botanicals offer a unique opportunity to explore novel compounds to prevent and treat various clinical disorders as well as understand their mode of action so that new …

Design And Manufacture Of Mesoscale Robot-Actuated Surgical Instruments, Clayton L. Grames

Theses and Dissertations

Minimally Invasive Surgery (MIS) is a growing field including both laparoscopic androbotic operations. Surgeons and engineers are making continual efforts to reduce the negative effects of procedures on patients. Reducing the size of the surgical instruments is one effective method pursued in this effort. When the instruments approach 3 mm in diameter, they reach a threshold where the entry incisions can be small enough that no scar is left on the patient. Laparoscopic instruments on this scale exist but typically lack wrist articulation and only have 1 degree of freedom (DoF). Alternatively, robotic surgical instruments can achieve high levels of …

A Multiagent Approach Towards Solving Complex Problems Of Sociotechnical Systems, Hongying Du

Theses and Dissertations

Complex resource allocation problems arise due to complex human societies and scarce resources to be distributed. Scarce resources could be food, water, and energy. Meanwhile, the size of the problem, the intersection of different areas, and possible global consequences all add to the complexity of the problems, which makes it difficult for humans to solve the problems by themselves.

For all these reasons, humans need technical help to tackle complex problems. Since humans participating in the problems usually own part of the information about the problems, and no one may see the whole picture of the problems, it is natural …

Cost Constrained Improvements To The Military Retirement System, Cynthia A. Brown

Theses and Dissertations

This research studies possible changes to the current military retirement system. The current military retirement system refers to the system provided under the Military Reform Act of 1986, A new system is proposed which would provide the retiree with four options. Option 1 would provide a pay annuity and medical benefits to the retiree (this is the current system). Option 2 would provide a pay lump sum in place of the, annuity and would offer medical benefits. Option 3 would offer the pay annuity but give a medical lump sum amount in place of the medical benefit. Finally, option 4 …