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Full-Text Articles in Engineering

Retrofitting A Stereolithography System Within A Laminar Flow Hood, Mahesh Pandurang Tonde Jan 2009

Retrofitting A Stereolithography System Within A Laminar Flow Hood, Mahesh Pandurang Tonde

Open Access Theses & Dissertations

This research focused on retrofitting the stereolithography (SL), a rapid prototyping technology, inside a laminar flow hood to provide an aseptic, particulate-free environment for scaffold fabrication. Two of the important objectives of this project were to retrofit the commercial SLA 250/30 inside a laminar flow hood to demonstrate that the manufacturability of the Bio-SL system was comparable to original SLA 250 system and to conduct the sterility test on fabricated scaffolds to show that the laminar flow hood was able to provide an aseptic, particulate-free environment for the fabrication.


Exploring Poly(Ethylene Glycol) As A Suitable Material For Peripheral Nerve Regeneration Scaffolds Manufactured By Stereolithography, Nubia Zuverza Jan 2009

Exploring Poly(Ethylene Glycol) As A Suitable Material For Peripheral Nerve Regeneration Scaffolds Manufactured By Stereolithography, Nubia Zuverza

Open Access Theses & Dissertations

One of the challenges in tissue engineering is to have spatial and temporal control over the biological elements within a scaffold used to guide regeneration for example of transected nerves. Some of the physical and chemical characteristics to regulate include incorporation of bioactive domains and release of chemical signals. This study presents the use of stereolithography (SL) to incorporate localized domains for cell adhesion in addition to include releasable nerve growth factor (NGF) in the process of building poly(ethylene glycol)diacrylate (PEGda) hydrogel scaffolds. Besides providing sites for cell attachment, an ideal nerve guidance conduit (NGC) should be able to release …