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Perforation Of Arterial Tissue Using Kilohertz Frequency Ultrasound Delivered Via Wire Waveguides, Mark Wylie, Garrett Mcguinness, Graham Gavin
Perforation Of Arterial Tissue Using Kilohertz Frequency Ultrasound Delivered Via Wire Waveguides, Mark Wylie, Garrett Mcguinness, Graham Gavin
Conference Papers
An emerging technology proposes the use of low frequency-high power ultrasound transmitted via wire waveguides for the disruption and ablation of atherosclerotic lesions, more specifically advanced fibrous or calcified plaques such as chronic total occlusions (CTO). This energy delivery selectively ablates rigid diseased tissue by means of direct mechanical contact, cavitation and other forces generated by the intense dynamic pressure fields generated.
The first clinical device using this energy delivery was granted FDA approval in 2007 [1] for the ablation of CTOs and most research to date has focused on ablation and disruption of hard, fibrous or calcified tissues [2]. …