Engineering Commons^™

Biomarkers Of Fatigue: Metabolomics Profiles Predictive Of Cognitive Performance, Nicholas J. Delraso, Deirdre A. Mahle, John J. Schlager, Donald L. Harville, Scott R. Chaiken, Danelle K. Roddy, Mari Chamberlain, Paul E. Anderson, Nicholas V. Reo, Michael L. Raymer, Isaie Sibomana

Computer Science and Engineering Faculty Publications

Cognitive performance and fatigue are well known to be inversely related. Continuous and sustained actions in operational environments typically lead to reduced sleep normally required to perform optimally. These operational environments subject the warfighter to intense physical and mental exertion. Because fatigue continues to be an occupational hazard, leading to cognitive defects in performance, there has been a recognized need for real-time detection technologies that minimize fatigue-induced mishaps. I the current study, 23 subjects were subjected to 36h of sleep deprivation and cognitive psychomotor vigilance and automated neuropsychological assessment metric tests were conducted over the last 24 h of sleep …