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Full-Text Articles in Engineering

A Simple, Realistic Walled Phantom For Intravascular And Intracardiac Applications., Hareem Nisar, John Moore, Roberta Piazza, Efthymios Maneas, Elvis C S Chen, Terry M Peters Sep 2020

A Simple, Realistic Walled Phantom For Intravascular And Intracardiac Applications., Hareem Nisar, John Moore, Roberta Piazza, Efthymios Maneas, Elvis C S Chen, Terry M Peters

Robarts Imaging Publications

PURPOSE: This work aims to develop a simple, anatomically and haptically realistic vascular phantom, compatible with intravascular and intracardiac ultrasound. The low-cost, dual-layered phantom bridges the gap between traditional wall-only and wall-less phantoms by showing both the vessel wall and surrounding tissue in ultrasound imaging. This phantom can better assist clinical tool training, testing of intravascular devices, blood flow studies, and validation of algorithms for intravascular and intracardiac surgical systems.

METHODS: Polyvinyl alcohol cryogel (PVA-c) incorporating a scattering agent was used to obtain vessel and tissue-mimicking materials. Our specific design targeted the inferior vena cava and renal bifurcations which were …


A 3d Printed Axon-Mimetic Diffusion Mri Phantom, Tristan K. Kuehn Aug 2020

A 3d Printed Axon-Mimetic Diffusion Mri Phantom, Tristan K. Kuehn

Electronic Thesis and Dissertation Repository

Diffusion MRI is used to non-invasively characterize the microstructure of the brain. However, the accuracy of the characterization is difficult to verify because no other non-invasive imaging modality provides the same information. This thesis presents a novel 3D printed axon-mimetic (3AM) diffusion MRI phantom, a synthetic object designed to mimic the brain's microstructure.

The phantoms were characterized using microscopy, synchrotron micro-computed tomography, and diffusion MRI, and found to have sufficiently axon-mimetic properties to be useful as diffusion MRI phantoms. A set of phantoms designed to have anatomically realistic and complex fibre structures was used to test the response of diffusion …