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Full-Text Articles in Engineering

Stem Cell Induction Via Inkjet-Mediated Gene Transfection, Gilbert Paquian Jr. Jan 2016

Stem Cell Induction Via Inkjet-Mediated Gene Transfection, Gilbert Paquian Jr.

Open Access Theses & Dissertations

In 2009 and 2011, it was shown that micropores in the cell membrane that form during inkjet cell printing are a potential vector for gene transfection1,2. These papers showed that porcine aortic endothelial cells and Chinese hamster ovary cells were coprinted with green fluorescent protein-coding (GFP) plasmids onto collagen or gelatin "biopaper" substrates. Printed cells showed a viability of ~90% with transfection efficiencies ranging from 2-30%1,2. Using inkjet-mediated gene transfection (IMGT) to insert a plasmid coding for the Yamanaka stem cell induction factors, it may be possible to offset common drawbacks of the induction process, such as low efficiency, throughput, …


Liquid-Phase Exfoliation Of Two-Dimensional Graphite For Ink-Jet Printing, Monica Michel Jan 2016

Liquid-Phase Exfoliation Of Two-Dimensional Graphite For Ink-Jet Printing, Monica Michel

Open Access Theses & Dissertations

Over the last decade, the study of two-dimensional (2D) materials has seen an incredible growth due to their unique thermal, mechanical and electronic properties. Solution phase manufacturing offers a way in which they can be produced at large scale by creating dispersions from the exfoliated material. Once created, different options for assembling devices exist. One technique for large scale manufacturing of materials in this form is ink-jet printing, which is a form of additive manufacturing that has proven to be attractive for the printed electronics industry. One challenge that ink-jet printing still faces is the shortage of inks with appropriate …