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Full-Text Articles in Engineering

Rational Design And Synthesis Of Biodegradable Polyurethane Based Biomaterials, Cancan Xu Dec 2018

Rational Design And Synthesis Of Biodegradable Polyurethane Based Biomaterials, Cancan Xu

Bioengineering Dissertations

Biodegradable polyurethanes have been applied in biomedical field since 1960s. In recent years, biodegradable polyurethanes have been widely investigated for tissue repair and regeneration because of their good mechanical properties, elasticity, biodegradability, biocompatibility and processability. Compared with some commonly used biodegradable polymers, such as poly(glycolide) (PGA), poly(lactide) (PLA), poly(ε-caprolactone) (PCL) and polyhydroxyalkanoates (PHA), the favorable aspects of biodegradable polyurethane are its mechanical, physicochemical and biological properties can be tailored by varying the three blocks in polyurethane backbone, diisocyanate, diol and chain extender. In this thesis, we focus on the development of different functional biodegradable polyurethanes to study their structure-property relationships …


Osteogenic Differentiation In Preosteoblast Mc3t3-E1 Cells Induced By Beta Tricalcium Phosphate Bioglass Composite, Chien-Ning Yao Aug 2016

Osteogenic Differentiation In Preosteoblast Mc3t3-E1 Cells Induced By Beta Tricalcium Phosphate Bioglass Composite, Chien-Ning Yao

Material Science and Engineering Theses

The use of bioactive material from bioceramic and composite components to support bone cell and tissue growth is an interesting area of medical field. Calcium phosphate ceramics are biocompatible and may develop interactions with human living bone tissues. Bioactive calcium phosphates, beta -tricalcium phosphate (β-TCP), have been intensively investigated as the cell scaffold for bone tissue engineering because it is well recognized that they are compatible to natural bone tissue and osteoconductive. In this research we will discuss two types of biomaterial with different kind of composition—(a) a cement type and (b)a scaffold type of biomaterial that can be applied …