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Full-Text Articles in Engineering

Small Molecule Drug Release Form In Situ Forming Degradable Scaffolds Incorporating Hydrogels And Bioceramic Microparticles, David A. Puleo, Todd A. Milbrandt, J. Zach Hilt, Paul Fisher, Vishwas Talwalkar Jun 2020

Small Molecule Drug Release Form In Situ Forming Degradable Scaffolds Incorporating Hydrogels And Bioceramic Microparticles, David A. Puleo, Todd A. Milbrandt, J. Zach Hilt, Paul Fisher, Vishwas Talwalkar

Biomedical Engineering Faculty Patents

The present invention relates to an injectable system combining a hydrogel, a bioceramic and a degradable matrix that provides for sustained drug delivery and structural support to recovering tissue, such as bone and the periodontium.


Water Purification Device And A Method Of Decontaminating A Water Supply, Dibakar Bhattacharyya, Li Xiao Jun 2020

Water Purification Device And A Method Of Decontaminating A Water Supply, Dibakar Bhattacharyya, Li Xiao

Chemical and Materials Engineering Faculty Patents

A water purification device is provided in the form of a hydrogel matrix containing immobilized nanoparticles that are directly synthesized in-situ in the hydrogel matrix. The hydrogel matrix is temperature sensitive, such that swelling draws in pollutants that are captured by the nanoparticles, while deswelling releases purified water. A related method of decontaminating the water supply contaminated with a target pollutant is also disclosed.


Electrophoresis In Heterogeneous Hydrogels And Applications In Surface Patterning, Ning Ge Jan 2020

Electrophoresis In Heterogeneous Hydrogels And Applications In Surface Patterning, Ning Ge

Theses and Dissertations--Mechanical Engineering

The creation of chemical micropatterns on surfaces makes it possible to add unique chemical functionality to surfaces, modifying properties such as wettability, or even adding the ability to selectively bind other molecules. The creation of biochemical surface patterning in particular is useful in a variety of fields including tissue engineering and highthroughput drug screening. There are many existing surface patterning techniques which focus on precise control over the patterned geometry, even down to submicron scale features, but they do not allow local control over chemical concentration. So the results are high resolution patterns with binary concentration. There are also existing …