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Characterization Of Boron/Iron-Oxide Core/Shell Structure For Boron Neutron Capture Therapy By Stem/Eels-Xeds And Mössbauer Spectroscopy, Mason Douglas Hayward
Characterization Of Boron/Iron-Oxide Core/Shell Structure For Boron Neutron Capture Therapy By Stem/Eels-Xeds And Mössbauer Spectroscopy, Mason Douglas Hayward
Graduate Research Theses & Dissertations
Boron/iron-oxide core/shell structured nanoparticles were characterized for application in boron neutron capture therapy (BNCT). BNCT is a cancer treatment method using the ability of boron to absorb thermal neutrons and a proposed drug delivery system utilizing an external magnetic field to direct the boron nanoparticles to targeted cancer sites and to extract the used nanoparticles after treatment. Boron nanoparticles were magnetically functionalized by encapsulating with an iron oxide shell. As such the exact composition, size distribution and oxidation states of the core/shell structures can affect treatment efficacy. Characterization was done by electron energy loss spectroscopy (EELS) and x-ray energy dispersive …