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Fabrication Of Hydroxyapatite-Biodegradable Polymer Scaffolds By Electrospinning For Potential Bone Tissue Application, Satomi Suzuki
Fabrication Of Hydroxyapatite-Biodegradable Polymer Scaffolds By Electrospinning For Potential Bone Tissue Application, Satomi Suzuki
Theses
The purpose of this study is to determine the potential of combining hydroxyapatite (HA) and polymers to form synthetic composite materials used for bone tissue engineering applications. In this study, ceramic-biodegradable polymer composites are fabricated by electrospinning method. The biodegradable polymers used are poly(L-lactic acid) (PLLA), and poly(lactide-co-glycolide) (PLGA). Two types of HA-polymer solutions are first prepared to achieve HA weight percentage of 0, 10, and 25%of the total combined weight of HA and PLLA, and HA and PLGA. The solutions are electrospun to form nanofibrous mats incorporated with HA powder. A biomimetic process was also conducted as a …
Fabrication Of Aligned Nanofiber Yarns, Mats And Isolation Of Single Nanofiber In Electrospinning, Venkatesh T. Nathilvar
Fabrication Of Aligned Nanofiber Yarns, Mats And Isolation Of Single Nanofiber In Electrospinning, Venkatesh T. Nathilvar
Theses
Electrospinning has been extensively used as an effective technique for the fabrication of submicron and nanometer scale polymeric fibers. In spite of technological advances in electrospinning, creating a highly aligned fiber structure is a tough target to be achieved because of the chaotic motion of the electrospinning jet. In this study, two different techniques have been adopted to form a highly aligned nanofibrous scaffolds. Using these methods highly aligned fiber yams and mats are produced from Cellulose Acetate (CA) in a mixed solvent of acetone and water. In both the techniques the nanofibers suspend over the gap in a highly …