Engineering Commons^™

Development Of Confocal Imaging Techniques For Probing Interfacial Dynamics In Microscale, Gas-Liquid, Two-Phase Flow, Joseph E. Hernandez

Dissertations, Master's Theses and Master's Reports - Open

Micro-scale, two-phase flow is found in a variety of devices such as Lab-on-a-chip, bio-chips, micro-heat exchangers, and fuel cells. Knowledge of the fluid behavior near the dynamic gas-liquid interface is required for developing accurate predictive models. Light is distorted near a curved gas-liquid interface preventing accurate measurement of interfacial shape and internal liquid velocities. This research focused on the development of experimental methods designed to isolate and probe dynamic liquid films and measure velocity fields near a moving gas-liquid interface. A high-speed, reflectance, swept-field confocal (RSFC) imaging system was developed for imaging near curved surfaces.

Experimental studies of dynamic gas-liquid …

Utilizing Dielectrophoresis To Determine The Physiological Differences Of Eukaryotic Cells, Tayloria Nicole Gail Adams

Dissertations, Master's Theses and Master's Reports - Open

Type 1 diabetes affects over 108,000 children, and this number is steadily increasing. Current insulin therapies help manage the disease but are not a cure. Over a child’s lifetime they can develop kidney disease, blindness, cardiovascular disease and many other issues due to the complications of type 1 diabetes. This autoimmune disease destroys beta cells located in the pancreas, which are used to regulate glucose levels in the body. Because there is no cure and many children are affected by the disease there is a need for alternative therapeutic options that can lead to a cure.

Human mesenchymal stem cells …

Alternating Current Dielectrophoretic Manipulation Of Erythrocytes In Medical Microdevice Technology, Kaela M. Leonard

Dissertations, Master's Theses and Master's Reports - Open

Medical microdevices have gained popularity in the past few decades because they allow the medical laboratory to be taken out into the field and for disease diagnostics to happen with a smaller sample volume, at a lower cost and much faster. Blood is the human body's most readily available and informative diagnostic fluid because of the wealth of information it provides about the body's general health including enzymatic, proteomic and immunological states. The purpose of this project is to optimize operating conditions and study ABO-Rh erythrocytes dielectrophoretic responses to alternating current electric signals. The end goal of this project is …