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Engineering Conferences International

2017

Integrated DSP

Articles 1 - 2 of 2

Full-Text Articles in Engineering

Supervisory Control Of Integrated Continuous Downstream Processes, Bernt Nilsson, Niklas Andersson, Joaquin Gomis Fons, Anton Löfgren Sep 2017

Supervisory Control Of Integrated Continuous Downstream Processes, Bernt Nilsson, Niklas Andersson, Joaquin Gomis Fons, Anton Löfgren

Integrated Continuous Biomanufacturing III

Smart downstream processing can be performed with a sequence of integrated purification steps, which minimize the number of storage tanks and reduce hold-up time. The result is an integrated unit operation sequence that performs straight through processing of the target protein, with minimal time from expression to formulation. This downstream processing technique is well suited to be connected to a continuous upstream process based on perfusion. To develop these kinds of processes it is important to do studies in small-scale in a convenient way. This paper presents a methodology for supervisory control of integrated continuous downstream processes in lab-scale. A …


Supervisory Control Of Integrated Continuous Downstream Processes, Bernt Nilsson, Anton Löfgren, Joaquin Gomis Fons, Niklas Andersson, Lotta Berghard Sep 2017

Supervisory Control Of Integrated Continuous Downstream Processes, Bernt Nilsson, Anton Löfgren, Joaquin Gomis Fons, Niklas Andersson, Lotta Berghard

Integrated Continuous Biomanufacturing III

Smart downstream processing can be performed with a sequence of integrated purification steps, which minimize the number of storage tanks and reduce hold-up time. The result is an integrated unit operation sequence that performs straight through processing of the target protein, with minimal time from expression to formulation. This downstream processing technique is well suited to be connected to a continuous upstream process based on perfusion. To develop these kinds of processes it is important to do studies in small-scale in a convenient way. This paper presents a methodology for supervisory control of integrated continuous downstream processes in lab-scale. A …