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Fabrication And Characterization Of Multi-Functional Non-Spherical Particles Via Mechanical Deformation, Venkata Shilpa Varahagiri
Fabrication And Characterization Of Multi-Functional Non-Spherical Particles Via Mechanical Deformation, Venkata Shilpa Varahagiri
All Theses
Nanoparticles bridge the gap between bulk materials and molecules. They possess exciting but contrasting mechanical, chemical, magnetic and optical properties when compared to their bulk counterparts due to their shape and size. When the size of noble metal nanoparticles is reduced to less than the wavelength of light, the particles intensely absorb and scatter light at wavelengths that depend on the particle size, shape, and local dielectric environment due to Localized Surface Plasmon Resonance (LSPR) modes. Recently, plasmonic particles have been used in a wide variety of sensor and optical device applications including immunoassays and surface enhanced Raman spectroscopy substrates. …
Application Of Nanotechnology For Targeted Delivery Of Antibacterial Enzymes And For Enzyme-Based Coatings On Medical Devices And Implants, Rohan Satishkumar
Application Of Nanotechnology For Targeted Delivery Of Antibacterial Enzymes And For Enzyme-Based Coatings On Medical Devices And Implants, Rohan Satishkumar
All Dissertations
The frequency of S. aureus infection and subsequent biofilm formation associated with vascular catheterization has been increasing in recent years and often begins as a local colonization at the site of the catheter insertion. Antimicrobial enzymes and peptides, which are effective against a broad range of pathogens and low rates of resistance, have attracted attention as promising alternative candidates in treatment of infections caused by antibiotic resistant bacteria. The use of nanoparticles as carriers for enzymes, in addition to their size, charge, high surface area per volume etc. offers targeted delivery of enzymes to pathogenic bacteria. We proposed to use …