Engineering Commons^™

Post-Acquisition Processing Confounds In Brain Volumetric Quantification Of White Matter Hyperintensities, Ahmed A. Bahrani, Omar M. Al-Janabi, Erin L. Abner, Shoshana H. Bardach, Richard J. Kryscio, Donna M. Wilcock, Charles D. Smith, Gregory A. Jicha

Neurology Faculty Publications

BACKGROUND: Disparate research sites using identical or near-identical magnetic resonance imaging (MRI) acquisition techniques often produce results that demonstrate significant variability regarding volumetric quantification of white matter hyperintensities (WMH) in the aging population. The sources of such variability have not previously been fully explored.

NEW METHOD: 3D FLAIR sequences from a group of randomly selected aged subjects were analyzed to identify sources-of-variability in post-acquisition processing that can be problematic when comparing WMH volumetric data across disparate sites. The methods developed focused on standardizing post-acquisition protocol processing methods to develop a protocol with less than 0.5% inter-rater variance.

RESULTS: A series …

Investigation Of The Effect Of Age On Regenerative Outcomes Following Treatment Of Volumetric Muscle Loss Injuries, John Taehwan Kim

Graduate Theses and Dissertations

Volumetric muscle loss (VML) is a traumatic injury in skeletal muscle resulting in the bulk loss of more than 20% of the muscle’s volume. Included in the bulk loss of muscle is the skeletal muscle niche comprised of nerve bundles, vasculature, local progenitor cells, basal lamina, and muscle fibers, overwhelming innate repair mechanisms. The hallmark of VML injury is the excessive accumulation of non-contractile, fibrotic tissue and permanent functional deficits. Though predominant in the younger demographic, the elderly population is also captured within VML injuries. There are many factors that change with aging in skeletal muscle that may further hinder …

Distinct Patterns Of Default Mode And Executive Control Network Circuitry Contribute To Present And Future Executive Function In Older Adults, Christopher A. Brown, Frederick A. Schmitt, Charles D. Smith, Brian T. Gold

Neuroscience Faculty Publications

Executive function (EF) performance in older adults has been linked with functional and structural profiles within the executive control network (ECN) and default mode network (DMN), white matter hyperintensities (WMH) burden and levels of Alzheimer's disease (AD) pathology. Here, we simultaneously explored the unique contributions of these factors to baseline and longitudinal EF performance in older adults. Thirty-two cognitively normal (CN) older adults underwent neuropsychological testing at baseline and annually for three years. Neuroimaging and AD pathology measures were collected at baseline. Separate linear regression models were used to determine which of these variables predicted composite EF scores at baseline …

Short Beam Shear Strength Evaluations Of Gfrp Composites: Correlations Through Accelerated And Natural Aging, William Todd Barker

Graduate Theses, Dissertations, and Problem Reports

Fiber Reinforced Polymers (FRP) composites have been materials of interest in replacing or reinforcing steel, wood, and concrete, but lack of understanding of degradation under physical and chemical aging is a main concern. Through many years of research, the understanding of aging or durability of GFRPs has improved. To be able to evaluate aging related degradation rates, an accelerated aging methodology under varying environments is introduced. Accelerated aging is a concept used to age composites in a lab controlled environment under varying pH conditions (2 to 13) and temperatures (~ -20° to +160°F). Once acceleratedly aged testing is completed, Arrhenius …

Agenator: An Open Source Computer-Controlled Dry Aging System For Beef, Soon Kiat Lau, Felipe Azevedo Ribeiro, Jeyamkondan Subbiah, Chris R. Calkins

Department of Biological Systems Engineering: Papers and Publications

Dry aging of beef is a process where beef is exposed to a controlled environment with the ultimate goal of drying the beef to improve its quality and value. Comprehensive investigations into the effects of various environmental conditions on dry aging are crucial for understanding and optimizing the process, but the lack of affordable equipment focused on data collection makes it difficult to do so. The Agenator was thus developed as an open source system with a suite of features for investigating dry aging such as: measuring and recording relative humidity, temperature, mass, air velocity, and fan rotational speed; precise …

A Computational Study On Aging Effect For Facial Expression Recognition, Elena Sönmez

Turkish Journal of Electrical Engineering and Computer Sciences

This work uses newly introduced variations of the sparse representation-based classifier (SRC) to challenge the issue of automatic facial expression recognition (FER) with faces belonging to a wide span of ages. Since facial expression is one of the most powerful and immediate ways to disclose individuals? emotions and intentions, the study of emotional traits is an active research topic both in psychology and in engineering fields. To date, automatic FER systems work well with frontal and clean faces, but disturbance factors can dramatically decrease their performance. Aging is a critical disruption element, which is present in any real-world situation and …

Quantifying The Seismic Vulnerability Of Bridges In Low To Moderate Seismicity Regions, John Edward Lens

Graduate College Dissertations and Theses

The U.S. Congressional Research Service issued a report for Congress in May 2016, entitled” Earthquake Risk and U.S. Highway Infrastructure: Frequently Asked Questions” which highlighted the absence of a national database on the status of seismic vulnerability of bridges or other infrastructure, and thus no estimate of costs to retrofit vulnerable bridges. Low to moderate seismicity regions exist in each of the continental United States, with over 30 states having mostly or entirely low-to-moderate seismicity. Resources at state transportation agencies and municipalities are focused on higher seismicity regions, creating a gap in quantifying the system-wide seismic vulnerability despite an overall …