Open Access. Powered by Scholars. Published by Universities.®
- Discipline
- Publication Type
Articles 1 - 8 of 8
Full-Text Articles in Engineering
Influence Of Fibroblasts On Functional Arteriogenesis In A Murine Chronic Hindlimb Ischemia Model, Ashli A. Santos
Influence Of Fibroblasts On Functional Arteriogenesis In A Murine Chronic Hindlimb Ischemia Model, Ashli A. Santos
Biomedical Engineering
Peripheral arterial occlusive disease (PAOD) occurs when there is a narrowing or blockage – usually a buildup of plaque - within the arteries that reduces blood flow to tissues which can chronic ischemia. As with most diseases, early detection and proactive treatment are important to maximize prognosis. Exercise effectively treats PAOD, but due to ischemic pain in the limbs, or intermittent claudication (IC), exercise can become painful and difficult. Due to the buildup of plaque, occlusions create an ischemic environment that changes the pressure distribution in collateral networks and increases the shear stress in transverse collaterals. Those two responses signal …
Elbow And Shoulder Joint Torques Are Correlated With Body Mass Index But Not Game Pitch Count In Youth Baseball Pitchers, Jim Douglas Darke, Eshan M. Dandekar, Arnel Aguinaldo, Scott Hazelwood, Stephen M. Klisch
Elbow And Shoulder Joint Torques Are Correlated With Body Mass Index But Not Game Pitch Count In Youth Baseball Pitchers, Jim Douglas Darke, Eshan M. Dandekar, Arnel Aguinaldo, Scott Hazelwood, Stephen M. Klisch
Biomedical Engineering
The number of ulnar collateral ligament (UCL) reconstructive (i.e. “Tommy John”) surgeries performed on youth baseball pitchers have more than doubled since 2000 [1]. Routinely pitching while fatigued is considered a leading factor associated with UCL injuries; adolescent pitchers who had elbow or shoulder surgery were 36 times more likely to have routinely pitched with arm fatigue [1]. MLB/USA Baseball Pitch Smart guidelines limit 9-10 yr. old pitchers to a maximum 75 pitches per game, a figure based on long-term studies related to injury prevention [2]. Several studies have shown that pitching kinematics (e.g. elbow flexion/extension and pronation/supination, scapulothoracic internal-external …
Knee Biomechanics During Cycling Are Similar For Normal Weight And Obese Subjects, Juan D. Gutierrez-Franco, Jordan Skaro, Scott Hazelwood, Stephen M. Klisch
Knee Biomechanics During Cycling Are Similar For Normal Weight And Obese Subjects, Juan D. Gutierrez-Franco, Jordan Skaro, Scott Hazelwood, Stephen M. Klisch
Biomedical Engineering
Osteoarthritis (OA) is a degenerative disease of cartilage and bone tissue, and is linked to more than 70% of total hip and knee replacements [1]. In 1994 the direct and indirect costs of OA in the United States were $155 billion [2] and in 2006 OA resulted in approximately $10.5 billion in hospital charges [3]. Obesity is a risk factor for OA [1, 3, 4], likely due to increased knee loading [5, 6] and varus malalignment [7] in gait. Seated cycling has been recommended as a weight-loss exercise with lower knee loads than walking or jogging [8]. However, lack of …
Principal Component Analysis Of Gait And Cycling Experiments: Crosstalk Error Reduction And Corrected Knee Axes, Jordan Skaro, Harsh Goel, Scott Hazelwood, Stephen M. Klisch
Principal Component Analysis Of Gait And Cycling Experiments: Crosstalk Error Reduction And Corrected Knee Axes, Jordan Skaro, Harsh Goel, Scott Hazelwood, Stephen M. Klisch
Biomedical Engineering
Crosstalk is a leading source of error in motion analysis [1-2]. Due to incorrect flexion axis direction that develops from marker placement error, crosstalk results in a strong, anatomically incorrect correlation between flexion-extension (FE) and adduction-abduction (AA) motions [1-2]. Thus, crosstalk limits the ability of biomechanical models to reflect the “true” motion of the knee. Principal Component Analysis (PCA) has been proposed as a post-hoc correction for crosstalk in prior gait studies [1-2]; however, previous studies have not proposed a method to determine PCA corrected knee axes. Further, it is not clear how PCA should be implemented in motion analysis …
Emg-Driven Inverse Dynamic Analysis Of Knee Contact Forces During Gait And Cycling Using Opensim, Megan V. Pottinger, Katherine Mavrommati, Scott Hazelwood, Stephen M. Klisch
Emg-Driven Inverse Dynamic Analysis Of Knee Contact Forces During Gait And Cycling Using Opensim, Megan V. Pottinger, Katherine Mavrommati, Scott Hazelwood, Stephen M. Klisch
Biomedical Engineering
Joint contact forces determine the loading experienced by cartilage tissue and, thus, may be used to predict risk of cartilage tissue damage and osteoarthritis (OA). Participating in low impact and/or non-weight bearing activities such as cycling may help reduce knee OA risk by limiting forces exerted during exercise [1]. Cycling is a common recommendation for rehabilitative or fitness sustainment exercise for select patients [1]. Although knee joint contact forces have been directly measured in gait and cycling using instrumented knee implants [2,3] and calculated in gait using EMG-driven analysis [4]; they have not been calculated in cycling using EMG-driven analysis. …
Redesign Of The Medtronic Kyphon Bone Cement Mixer For Vertebral Compression Fractures, Mollie Benson, Sarah Freesemann, Aj Konnath, Benjamin Murray
Redesign Of The Medtronic Kyphon Bone Cement Mixer For Vertebral Compression Fractures, Mollie Benson, Sarah Freesemann, Aj Konnath, Benjamin Murray
Biomedical Engineering
The complete senior project report was submitted to the project advisor and sponsor. The results of this project are of a confidential nature and will not be published at this time.
Wheelieking Trainer Project Report, Harold Hall Iii, Nathaniel Fox, Thomas Niemisto
Wheelieking Trainer Project Report, Harold Hall Iii, Nathaniel Fox, Thomas Niemisto
Biomedical Engineering
In this report we will detail the design and implementation process of the WheelieKing Trainer project, a device that helps people learn how to do wheelies on a bicycle by preventing backward falls. Formal project requirements are specified, followed by the ideation and iteration process to meet those requirements. The components and methods used to create the device are described in detail. The results of the development process and usage test results of the device are included. Appendices at the end of this report include references, supporting analyses, and project management and timeline details.
Isolation And Culture Of Myofiber-Derived Cells From The Extensor Digitorum Longus Muscle, Ethan M. Tietze
Isolation And Culture Of Myofiber-Derived Cells From The Extensor Digitorum Longus Muscle, Ethan M. Tietze
Biomedical Engineering
Peripheral arterial occlusive disease (PAOD) involves distal artery occlusion by atherosclerotic plaques, which restricts blood flow and leads to ischemia in downstream tissues. Increased blood flow through preexisting collateral vessels leads to increased shear stress that triggers an outward remodeling of the vessel called arteriogenesis. In some cases this natural compensatory mechanism is able to sufficiently restore blood flow following arterial occlusion. However, for many individuals this process is insufficient to relieve peripheral ischemia, and patients experience intermittent claudication, or limb pain with locomotion or exercise. Without treatment, reduced blood flow can lead to tissue necrosis and potentially amputation. The …