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Full-Text Articles in Engineering

Design And Scale-Up Of Production Scale Stirred Tank Fermentors, Ryan Z. Davis May 2010

Design And Scale-Up Of Production Scale Stirred Tank Fermentors, Ryan Z. Davis

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

In the bio/pharmaceutical industry, fermentation is extremely important in pharmaceutical development, and in microbial research. However, new fermentor designs are needed to improve production and reduce costs of complex systems such as cultivation of mammalian cells and genetically engineered micro-organisms. Traditionally, stirred tank design is driven by the oxygen transfer capability needed to achieve cell growth. However, design methodologies available for stirred tank fermentors are insufficient and many times contain errors. The aim of this research is to improve the design of production scale stirred tank fermentors through the development of dimensionless correlations and by providing information on aspects of …


Designing Of Energy Efficient Indoor Environments Using A Localized Radial Basis Function Meshless Method, Victor Huayamave Jan 2010

Designing Of Energy Efficient Indoor Environments Using A Localized Radial Basis Function Meshless Method, Victor Huayamave

Electronic Theses and Dissertations

Around the world, the energy over consumption issue has been one of the key socio-economic and political challenges, which has drastically worsened over the last few years. Over the years engineers and environmentalists have proposed several approaches to improve energy efficiency. One is to reduce energy demand by improving consumption habits and a second approach is to introduce the use of a "greener" concept by using biomaterials in a diverse and more efficient manner in engineering construction to create energy efficient environments. This work will investigate the effects of using "green" stabilized earth materials to provide and enhance thermal regulation …


Transitional Flow Prediction Of A Compressor Airfoil, Vivek Hariharan Jan 2010

Transitional Flow Prediction Of A Compressor Airfoil, Vivek Hariharan

University of Kentucky Master's Theses

The steady flow aerodynamics of a cascade of compressor airfoils is computed using a two-dimensional thin layer Navier-Stokes flow solver. The Dhawan and Narasimha transition model and Mayle‟s transition length model were implemented in this flow solver so that transition from laminar to turbulent flow could be included in the computations. A method to speed up the convergence of the fully turbulent calculations has been introduced. In addition, the effect of turbulence production formulations and including streamline curvature correction in the Spalart-Allmaras turbulence model on the transition calculations is studied. These transitional calculations are correlated with the low and high …


A Computational Study For The Utilization Of Jet Pulsations In Gas Turbine Film Cooling And Flow Control, Olga V. Kartuzova Jan 2010

A Computational Study For The Utilization Of Jet Pulsations In Gas Turbine Film Cooling And Flow Control, Olga V. Kartuzova

ETD Archive

Jets have been utilized in various turbomachinery applications in order to improve gas turbines performance. Jet pulsation is a promising technique because of the reduction in the amount of air removed from compressor, which helps to increase turbine efficiency. In this work two areas of pulsed jets applications were investigated, first one is film cooling of High Pressure Turbine (HPT) blades and second one is flow separation control over Low Pressure Turbine (LPT) airfoil using Vortex Generator Jets (VGJ) The inlet temperature to the HPT significantly affects the performance of the gas turbine. Film cooling is one of the most …


Computational Study Of Fluid-Valve Interaction Involving Deep Vein Thrombosis, Upendra Parimi Jan 2010

Computational Study Of Fluid-Valve Interaction Involving Deep Vein Thrombosis, Upendra Parimi

Open Access Theses & Dissertations

The venous valves in veins carry on the important function of eliminating the retrograde (re-verse) flow of blood in veins and help the veins to carry on their work effectively. The abnormal functioning of venous valves can cause deep vein thrombosis (DVT) which is a phenomena caused by clotting in deep veins. The importance of the thesis work lies in understanding the role of blood flow dynamics in Deep Vein Thrombosis (DVT). Elderly People and pregnant women are the ones who are most likely to develop DVT. It was determined from previous studies that women in their postpartum period are …