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Profiling The Neurovascular Cell Interactions In Alcohol Exposure And Hiv-1 Infection, Agnieszka Agas
Profiling The Neurovascular Cell Interactions In Alcohol Exposure And Hiv-1 Infection, Agnieszka Agas
Theses
Alcohol use is known to exacerbate the progression of human immunodeficiency virus associated acquired immunodeficiency syndrome or HIV/AIDS in the brain, known as the NeuroAIDS. The mechanisms of this accelerated progression are still poorly understood. The purpose of my thesis is to review the parameters contributing to the co-morbid effects of alcohol in the progression of NeuroAIDS. The first aim will evaluate the exacerbating effects of alcohol on HIV-1 transmission, infection, and the role of metabolic energy imbalance during NeuroAIDS progression, which will enable me to formulate the possible mechanism for NeuroAIDS progression. The second aim will help me establish …