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Full-Text Articles in Engineering
Effects Of Local Ph On The Formation And Regulation Of Cristae Morphologies, Dong Hoon Song, Jonghyun Park, Martin A. Philbert, Ann Marie Sastry, Wei Lu
Effects Of Local Ph On The Formation And Regulation Of Cristae Morphologies, Dong Hoon Song, Jonghyun Park, Martin A. Philbert, Ann Marie Sastry, Wei Lu
Mechanical and Aerospace Engineering Faculty Research & Creative Works
Cristae, folded subcompartments of the inner mitochondrial membrane (IMM), have complex and dynamic morphologies. Since cristae are the major site of adenosine triphosphate synthesis, morphological changes of cristae have been studied in relation to functional states of mitochondria. In this sense, investigating the functional and structural significance of cristae may be critical for understanding progressive mitochondrial dysfunction. However, the detailed mechanisms of the formation and regulation of these cristae structures have not been fully elucidated. Among the hypotheses concerning the regulation of cristae morphologies, we exclusively investigate the effects of the local pH gradient on the cristae morphologies by using …
Simulations Of Ion Thruster Plume Contamination With A Whole Grid Sputtered Mo Source Model, Daoru Frank Han, Joseph J. Wang
Simulations Of Ion Thruster Plume Contamination With A Whole Grid Sputtered Mo Source Model, Daoru Frank Han, Joseph J. Wang
Mechanical and Aerospace Engineering Faculty Research & Creative Works
A particle simulation based source model is developed to calculate the density distribution of the sputtered Mo atoms for a whole ion optics grid. The source model is used in PIC simulation of ion thruster plume contamination for 3-grid and 2-grid ion thrusters. The results show that the commonly used point-source approximation for sputtered Mo atoms is oversimplified and would lead to over-prediction of contamination deposition.
Inherent And Model-Form Uncertainty Analysis For Cfd Simulation Of Synthetic Jet Actuators, Daoru Frank Han, Serhat Hosder
Inherent And Model-Form Uncertainty Analysis For Cfd Simulation Of Synthetic Jet Actuators, Daoru Frank Han, Serhat Hosder
Mechanical and Aerospace Engineering Faculty Research & Creative Works
A mixed (aleatory and epistemic) uncertainty quantification (UQ) method was applied to computational uid dynamics (CFD) modeling of a synthetic jet actuator. A test case, (ow over a hump model with synthetic jet actuator control) from the CFDVAL2004 work-shop was selected to apply the Second-Order Probability framework implemented with a stochastic response surface obtained from Quadrature-Based Non-Intrusive Polynomial Chaos (NIPC). Three uncertainty sources were considered: (1) epistemic (model-form) uncertainty in turbulence model, (2) aleatory (inherent) uncertainty in free stream veloc-ity and (3) aleatory uncertainty in actuation frequency. Uncertainties in both long-time averaged and phase averaged quantities were quantified using a …