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Full-Text Articles in Engineering
Comparison Of Resting Energy Expenditure Between Cancer Subjects And Healthy Controls: A Meta-Analysis, Thi Yen Vi Nguyen, Marijka Batterham, Cheree Edwards
Comparison Of Resting Energy Expenditure Between Cancer Subjects And Healthy Controls: A Meta-Analysis, Thi Yen Vi Nguyen, Marijka Batterham, Cheree Edwards
Faculty of Engineering and Information Sciences - Papers: Part A
There is conflicting evidence surrounding the extent of changes in resting energy expenditure (REE) in cancer. This meta-analysis aimed to establish the mean difference in REE, as kilojoules per kilogram fat-free mass, among cancer patients when compared to healthy control subjects. The secondary aim was to determine differences among different cancer types. PubMed, Cochrane Library, Medline, Science Direct, Scopus, Web of Science, Wiley Online Library, and ProQuest Central were searched from the earliest records until March 2014. Studies were included if measured REE was reported as kilojoules or kilocalories per kilogram fat-free mass (FFM) in adult subjects with cancer. Twenty-seven …
Imaging Dose In Breast Radiotherapy: Does Breast Size Affect The Dose To The Organs At Risk And The Risk Of Secondary Cancer To The Contralateral Breast?, Vikneswary Batumalai, Alexandra Quinn, Michael Jameson, Geoff Delaney, Lois C. Holloway
Imaging Dose In Breast Radiotherapy: Does Breast Size Affect The Dose To The Organs At Risk And The Risk Of Secondary Cancer To The Contralateral Breast?, Vikneswary Batumalai, Alexandra Quinn, Michael Jameson, Geoff Delaney, Lois C. Holloway
Faculty of Engineering and Information Sciences - Papers: Part A
Correct target positioning is crucial for accurate dose delivery in breast radiotherapy resulting in utilisation of daily imaging. However, the radiation dose from daily imaging is associated with increased probability of secondary induced cancer. The aim of this study was to quantify doses associated with three imaging modalities and investigate the correlation of dose and varying breast size in breast radiotherapy. Methods: Planning computed tomography (CT) data sets of 30 breast cancer patients were utilised to simulate the dose received by various organs from a megavoltage computed tomography (MV-CT), megavoltage electronic portal image (MV-EPI) and megavoltage cone-beam computed tomography (MV-CBCT). …
Image Guidance During Breast Radiotherapy: A Phantom Dosimetry And Radiation-Induced Second Cancer Risk Study, A Quinn, L Holloway, Peter Metcalfe
Image Guidance During Breast Radiotherapy: A Phantom Dosimetry And Radiation-Induced Second Cancer Risk Study, A Quinn, L Holloway, Peter Metcalfe
Faculty of Engineering and Information Sciences - Papers: Part A
Imaging procedures utilised for patient position verification during breast radiotherapy can add a considerable dose to organs surrounding the target volume on top of therapeutic scatter dose. This study investigated the dose from a breast kilovoltage cone-beam CT (kV-CBCT), a breast megavoltage fan-beam CT (MV-FBCT), and a TomoDirectTM breast treatment. Thermoluminescent dosimeters placed within a female anthropomorphic phantom were utilised to measure the dose to various organs and tissues. The contralateral breast, lungs and heart received 0.40 cGy, 0.45 cGy and 0.40 cGy from the kV-CBCT and 1.74 cGy, 1.39 cGy and 1.73 cGy from the MV-FBCT. In comparison to …
Computer Aided Decision Support System For Cervical Cancer Classification, - Rahmadwati, Golshah Naghdy, Montserrat B. Ros, Catherine Todd
Computer Aided Decision Support System For Cervical Cancer Classification, - Rahmadwati, Golshah Naghdy, Montserrat B. Ros, Catherine Todd
Faculty of Engineering and Information Sciences - Papers: Part A
Conventional analysis of a cervical histology image, such a pap smear or a biopsy sample, is performed by an expert pathologist manually. This involves inspecting the sample for cellular level abnormalities and determining the spread of the abnormalities. Cancer is graded based on the spread of the abnormal cells. This is a tedious, subjective and timeconsuming process with considerable variations in diagnosis between the experts. This paper presents a computer aided decision support system (CADSS) tool to help the pathologists in their examination of the cervical cancer biopsies. The main aim of the proposed CADSS system is to identify abnormalities …
Microdosimetry For Targeted Alpha Therapy Of Cancer, Chen-Yu Huang, Susanna Guatelli, Brad Oborn, Barry J. Allen
Microdosimetry For Targeted Alpha Therapy Of Cancer, Chen-Yu Huang, Susanna Guatelli, Brad Oborn, Barry J. Allen
Faculty of Engineering and Information Sciences - Papers: Part A
Targeted alpha therapy (TAT) has the advantage of delivering therapeutic doses to individual cancer cells while reducing the dose to normal tissues. TAT applications relate to hematologic malignancies and now extend to solid tumors. Results from several clinical trials have shown efficacy with limited toxicity. However, the dosimetry for the labeled alpha particle is challenging because of the heterogeneous antigen expression among cancer cells and the nature of short-range, high-LET alpha radiation. This paper demonstrates that it is inappropriate to investigate the therapeutic efficacy of TAT bymacrodosimetry. The objective of this work is to review the microdosimetry of TAT as …