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Chemical Engineering

Computational fluid dynamics

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A Computational Fluid Dynamics Analysis Of The Temperature And Impurity Profiles In The Protodune-Sp Neutrino Detector, Jenna Harrison Jan 2022

A Computational Fluid Dynamics Analysis Of The Temperature And Impurity Profiles In The Protodune-Sp Neutrino Detector, Jenna Harrison

Electronic Theses and Dissertations

Computational fluid dynamics (CFD) models of the ProtoDUNE single-phase detector were developed, refined, and analyzed. The ProtoDUNE single-phase detector is a prototype detector that is part of the Deep Underground Neutrino Experiment, an international research collaboration aimed at better understanding neutrinos and the role they play in our universe. The ProtoDUNE single-phase detector is used to gather data and inform design changes for the full-sized far detector prior to its construction. The effects of certain geometric features and heat sources on the thermal profiles within the liquid region of the detector were investigated in a set of parametric studies. The …


Non-Invasive Detection And Assessment Of Coronary Stenosis From Blood Mean Residence Times., Javad Hashemi Dec 2019

Non-Invasive Detection And Assessment Of Coronary Stenosis From Blood Mean Residence Times., Javad Hashemi

Electronic Theses and Dissertations

Coronary artery stenosis is an abnormal narrowing of a coronary artery caused by an atherosclerotic lesion that reduces lumen space. Fractional flow reserve (FFR) is the gold standard method to determine the severity of coronary stenosis based on the determination of rest and hyperemic pressure fields, but requires an invasive medical procedure. Normal FFR is 1.0 and FFR RT, to account for varying volume and flow rate of individual segments. BloodRT was computed in 100 patients who had undergone the pressure-wire FFR procedure, and a threshold for BloodRT was determined to assess the physiological significance of a stenosis, …


Model Of A Tubular Perfusion Bioreactor Using Computational Fluid Dynamics., Matthew James Robeson 1991- Jul 2015

Model Of A Tubular Perfusion Bioreactor Using Computational Fluid Dynamics., Matthew James Robeson 1991-

Electronic Theses and Dissertations

Through recent years, many novel bioreactor designs for tissue engineering have emerged. The Tubular Perfusion System (TPS) is one such bioreactor for bone and cartilage tissue engineering. The TPS is a perfusion type bioreactor, in which media flows through a bed of scaffold beads. The advantage of this system over similar designs is that it requires no special fabrication techniques and operates at low pressure. Experimental trials have shown increased osteoblastic differentiation and mineralization of bone tissue grown using the TPS versus static culture. The effectiveness of the TPS in promoting osteoblastic differentiation is believed to be due to enhanced …


Cfd Modeling Of Entrance And Exit Geometries Of A Wind Speed Accelerator., David Russ May 2011

Cfd Modeling Of Entrance And Exit Geometries Of A Wind Speed Accelerator., David Russ

Electronic Theses and Dissertations

Current wind power technology is not economically feasible throughout most of the United States due to low average wind speeds. A design for a small-scale wind concentrator device suitable for use in areas of low wind velocity was tested using computational fluid dynamics (CFD). Using a novel approach, the device seeks to accelerate incoming air above minimum velocities required for economical power generation. The novel approach employs a funnel shaped inlet with relief vents along the circumference, so as to alleviate backpressure. Both inlet and outlet sections utilize funnel shapes with both parabolic and hyperbolic regions. All geometry and mesh …