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Methods For Cancer Detection, Kimberly W. Anderson, Kimberly M.L. May, Leonidas G. Bachas
Methods For Cancer Detection, Kimberly W. Anderson, Kimberly M.L. May, Leonidas G. Bachas
Chemical and Materials Engineering Faculty Patents
A method is provided for detecting an analyte indicative of a cancer or a metastatic disease condition, which utilizes the ability of the analyte to induce permeability in a barrier. The method includes providing a biosensor having a barrier which is substantially impermeable to an ion, a permeable membrane which is selective for the ion, and a detector capable of detecting the ion. The biosensor is contacted with a sample including at least one of the ion and the analyte, wherein the analyte causes at least a portion of the ion to pass through the barrier and the membrane. Passage …