Engineering Commons^™

Concentration Field Based Micropore Flow Rate Measurements, Matia P. Edwards, Samuel F. D. J. Gómez, Michael S. H. Boutilier

Chemical and Biochemical Engineering Publications

Demand is growing for a larger catalogue of experimental techniques to measure flow rates through micro-/nanoscale systems for both fundamental research and device development. Flow emerging from a hole in a plane wall is a common system of interest in such work for its relevance to membrane separation. In this paper, we consider the possibility of measuring volume flow rates through small scale orifice plates from images of dye dispersions downstream. Based on approximate analytical solutions to the advection–diffusion equation, we show that, at low Reynolds numbers, the concentration in the nearly hemispherical plume that forms increases linearly with inverse …

Active Fluids: Rheological Properties And Response To Light Of Suspensions Of Synechocystis Sp. Cpcc 534, Zahra Habibi

Electronic Thesis and Dissertation Repository

Despite our current understanding of active fluid mechanics, more knowledge is required to fully understand their rheological properties, response to light, and details of the interactions between cells in diluted suspensions.

The focus of this thesis is on investigating the rheological properties of suspensions of cyanobacterium Synechocystis sp. CPCC 534 under shear, induced by stirring. Experiments were conducted at different stirring rates and results are compared with the stationary condition. A notable increase in growth and biomass of Synechocystis sp. under various shear conditions was observed and the yield was nearly doubled. Besides, the data showed Newtonian behavior for suspensions …

Development Of Multifunctional Drug Delivery Systems For Locoregional Therapy, Xinyi Li

Electronic Thesis and Dissertation Repository

Locoregional treatment is the specific delivery of therapeutics to their desired sites of action with minimized systemic adverse effects. In this approach, drug is administered through topical instillation, inhalation, intra-lesional or intra-arterial injection. Decades of experience in locoregional treatment have delivered meaningful benefits to patients with localized diseases (e.g., osteoarthritis, ocular disorders and liver cancers). However, improvements are required for this type of treatment to be more effective. For transarterial chemoembolization (TACE) therapy of hepatocellular carcinoma (HCC), the most current approaches do not allow repeat treatment as the drug delivery vehicle is not degradable. In addition, image contrast agents for …