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Full-Text Articles in Engineering
The Application Of Electric Cell-Substrate Impedance Sensing (Ecis) Biosensors, Xudong Zhang, Sunghoon Jang
The Application Of Electric Cell-Substrate Impedance Sensing (Ecis) Biosensors, Xudong Zhang, Sunghoon Jang
Publications and Research
Electric cell-substrate impedance sensing (ECIS) is a label-free and non-invasive technique for analyzing the activities and morphologies of cells. The ECIS sensors are able to measure the impedance spectroscopy of cells attaching on the sensor substrates. The cell activities and morphologies influence the measure impedance directly. Traditional toxicity analysis has complicated processes compared to biosensor-based analysis. In this study, the toxicity analysis was performed with biosensor based on ECIS technique. The experimental results show that the ECIS sensor is able to quickly distinguish the toxic and non-toxic substance.
Nano And Microsensors For Mammalian Cell Studies, Ioana Voiculescu, Masaya Toda, Naoki Inomata, Takahito Ono, Fang Li
Nano And Microsensors For Mammalian Cell Studies, Ioana Voiculescu, Masaya Toda, Naoki Inomata, Takahito Ono, Fang Li
Publications and Research
This review presents several sensors with dimensions at the nano- and micro-scale used for biological applications. Two types of cantilever beams employed as highly sensitive temperature sensors with biological applications will be presented. One type of cantilever beam is fabricated from composite materials and is operated in the deflection mode. In order to achieve the high sensitivity required for detection of heat generated by a single mammalian cell, the cantilever beam temperature sensor presented in this review was microprocessed with a length at the microscale and a thickness in the nanoscale dimension. The second type of cantilever beam presented in …