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California Polytechnic State University, San Luis Obispo

Biomedical Engineering

Series

2003

Articles 1 - 4 of 4

Full-Text Articles in Engineering

Neural Electronic Signal Detection Fidelity And Membrane Conductance, Robert B. Szlavik Oct 2003

Neural Electronic Signal Detection Fidelity And Membrane Conductance, Robert B. Szlavik

Biomedical Engineering

Abstract of paper presented at conference.


Development Of An Atrophic Nonunion Model And Comparison To A Closed Healing Fracture In Rat Femur, Takeshi Kokubu, David J. Hak, Scott J. Hazelwood, A. Hari Reddi May 2003

Development Of An Atrophic Nonunion Model And Comparison To A Closed Healing Fracture In Rat Femur, Takeshi Kokubu, David J. Hak, Scott J. Hazelwood, A. Hari Reddi

Biomedical Engineering

Although most fractures heal, some fail to heal and become nonunions. Many animal models have been developed to study problems of fracture healing. The majority of nonunion models have involved segmental bone defects, but this may not adequately represent the biologic condition in which nonunions clinically develop. The objective of the present study is to develop a nonunion model that better simulates the clinical situation in which there is soft tissue damage including periosteal disruption and to compare this model to a standard closed fracture model utilizing identical fracture stabilization, providing a similar mechanical environment. A total of 96 three …


Osteon Pullout In The Equine Third Metacarpal Bone: Effects Of Ex Vivo Fatigue, L. P. Hiller, S. M. Stover, V. A. Gibson, J. C. Gibeling, C. S. Prater, S. J. Hazelwood, O. C. Yeh, R. B. Martin May 2003

Osteon Pullout In The Equine Third Metacarpal Bone: Effects Of Ex Vivo Fatigue, L. P. Hiller, S. M. Stover, V. A. Gibson, J. C. Gibeling, C. S. Prater, S. J. Hazelwood, O. C. Yeh, R. B. Martin

Biomedical Engineering

An important concept in bone mechanics is that osteons influence mechanical properties in several ways, including contributing to toughness and fatigue strength by debonding from the interstitial matrix so as to "bridge" developing cracks. Observations of "pulled out" osteons on fracture surfaces are thought to be indicative of such behavior. We tested the hypothesis that osteon pullout varies with mode of loading (fatigue vs. monotonic), cortical region, elastic modulus, and fatigue life. Mid-diaphseal beams from the dorsal, medial, and lateral regions of the equine third metacarpal bone were fractured in four point bending by monotonic loading to failure under deflection …


Strategies For Improving Neural Signal Detection Using A Neural-Electronic Interface, Robert B. Szlavik Mar 2003

Strategies For Improving Neural Signal Detection Using A Neural-Electronic Interface, Robert B. Szlavik

Biomedical Engineering

There have been various theoretical and experimental studies presented in the literature that focus on interfacing neurons with discrete electronic devices, such as transistors. From both a theoretical and experimental perspective, these studies have emphasized the variability in the characteristics of the detected action potential from the nerve cell. The demonstrated lack of reproducible fidelity of the nerve cell action potential at the device junction would make it impractical to implement these devices in any neural prosthetic application where reliable detection of the action potential was a prerequisite. In this study, the effects of several different physical parameters on the …