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Full-Text Articles in Engineering

Pneumatic Latched Demultiplexer Circuit For Controlling Multi-Actuator Soft Robots, Arsh Noor Amin Jan 2023

Pneumatic Latched Demultiplexer Circuit For Controlling Multi-Actuator Soft Robots, Arsh Noor Amin

Master’s Theses

This thesis presents a novel method for controlling multi-actuator soft robots using pneumatic latched demultiplexer circuits implemented with monolithic membrane valves. The pneumatic circuits are designed to address the problems of heavy dependence on hard electrical components and lack of feasible multi-actuator soft robotic systems that limit the potential applications of soft robotics. The proposed pneumatic demultiplexers reduce the number of solenoid valves and electrical components required to drive soft robotic systems, making soft robot control mechanisms more compliant, scalable, and versatile. The thesis demonstrates the design, fabrication, and testing of 4-bit and n-bit pneumatic demultiplexer circuits that can control …


Modeling Small Molecule Elution From A Hydrogel Using A Microfluidic Technique, Stephanie Evans Jan 2011

Modeling Small Molecule Elution From A Hydrogel Using A Microfluidic Technique, Stephanie Evans

Master’s Theses

Drug release from a fluid-contacting biomaterial is simulated using a microfluidic device with channels defined by solute-loaded hydrogel. In order to mimic a drug delivery device, a solution of poly(ethylene glycol) diacrylate (PEG-DA), solute, and photoinitiator is cured inside a microfluidic device with a channel through the center ofthe hydrogel. As water is pumped through the channel, solute diffuses out of the hydrogel and into the water. Channel sizes within the devices range from 300 µm to 1000 µm to simulate vessels within the body. The properties of the PEG hydrogel were characterizedby the extent of crosslinking, the swelling ratio, …


A Microfluidic Method To Measure Diffusion In Hydrogels, Andrew Lee Litzenberger Jan 2010

A Microfluidic Method To Measure Diffusion In Hydrogels, Andrew Lee Litzenberger

Master’s Theses

A novel microfluidic method is proposed for studying diffusion of small molecules in a hydrogel. Microfluidic devices were prepared with semi-permeable microchannels defined by crosslinked poly(ethylene glycol) (PEG). Uptake of dye molecules from aqueous solutions flowing through the microchannels was observedoptically and diffusion of the dye into the hydrogel was quantified. To complement the diffusion measurements from the microfluidic studies, nuclear magnetic resonance(NMR) characterization of the diffusion of dye in the PEG hydrogels was performed. The diffusion of small molecules in a hydrogel is relevant to applications such asdrug delivery and modeling transport for tissue-engineering applications. The diffusion of small …