Engineering Commons^™

Openthinning: Fast 3d Thinning Based On Local Neighborhood Lookups, Tobias Post, Christina Gillmann, Thomas Wischgoll, Hans Hagen

Computer Science and Engineering Faculty Publications

3D Thinning is an often required image processing task in order to perform shape analysis in various applications. For researchers in these domains, a fast, flexible and easy to access implementation is required. Open source solutions, as the Insights Segmentation and Registration Toolkit (ITK), are often used for image processing and visualization tasks, due to their wide range of provided algorithms. Unfortunately, ITK’s thinning implementation is computational expensive and allows solely one specific thinning approach. Therefore, this work presents OpenThinning, an open source thinning solution for 3D image data. The implemented algorithm evaluates a moving local neighborhood to find deletable …

Cardiovascular Dieseases: From Data Generation To Analysis, Thomas Wischgoll

Computer Science and Engineering Faculty Publications

Cardiovascular diseases remain the leading cause of death in Western societies. This presentation will provide insight into the use of expert knowledge and models to derive diagnostic tools that have the potential to aid in the diagnosis of diffuse cardiovascular diseases that tend to be more difficult to detect in CT angiograms. In order to develop these methods more basic research is needed to prove the validity of the approach, including validation of accuracy as well as approach itself. For that, specimens of porcine hearts were prepared and then analyzed followed by a statistical comparison between computed and optical measurements. …

Super-Resolution Reconstruction Of Mri, Sara Gharabaghi, Thomas Wischgoll, Nasser H. Kashou

Computer Science and Engineering Faculty Publications

Magnetic Resonance Imaging (MRI) is a non-invasive technique that is used in clinical applications such as diseases diagnosis and monitoring and treatment progress. Although, MRI scans typically have high in-plane resolution but they have very poor resolution in slice direction. Furthermore, in some applications with limited acquisition time or where the subject is moving, increased slice thickness or inter-slice space (slice gaps) may be used which results in poor resolution MRI.

In this research, we propose a novel Super Resolution (SR) technique for reconstructing High-Resolution (HR) MRI using a sequence of orthogonal Low-Resolution (LR) MRI scans.

The resolution of this …

Hpc Enabled Data Analytics For High-Throughput High-Content Cellular Analysis, Ross A. Smith, Rhonda J. Vickery, Jack Harris, Sara Gharabaghi, Thomas Wischgoll, David Short, Robert Trevino, Steven A. Kawamoto, Thomas J. Lamkin, Kevin Schoen, Eric E. Bardes, Scott C. Tabar, Bruce J. Aronow

Computer Science and Engineering Faculty Publications

Biologists doing high-throughput high-content cellular analysis are generally not computer scientists or high performance computing (HPC) experts, and they want their workflow to support their science without having to be. We describe a new HPC enabled data analytics workflow with a web interface, HPC pipeline for analysis, and both traditional and new analytics tools to help them transition from a single workstation mode of operation to power HPC users. This allows the processing of multiple plates over a short period of time to ensure timely query and analysis to match potential countermeasures to individual responses.

A Semi-Automated Computer Program For Assessment Of Skeletal Maturity In Children, Sara Gharabaghi, Thomas Wischgoll

Computer Science and Engineering Faculty Publications

In pediatric patients, skeletal maturity is an important tool for detection of hormonal, growth or genetic disorders. The Fels method is a well-known visual assessment method in which the skeletal age is estimated by grading 98 skeletal indicators in the hand-wrist radiographic (x-ray) image. These indicators are features that reflect the three-dimensional shape of the bones and change during the maturation process. Generally, the Fels indicators could be categorized into three main groups of the status of ossification, the ratios of bone widths, and epiphysealdiaphyseal fusion.

Uncertainty-Awareness In Open Source Visualization Solutions, Christina Gillmann, Thomas Wischgoll, Hans Hagen

Computer Science and Engineering Faculty Publications

The popularity of open source tools is constantly increasing, as they offer the possibility to quickly create and use visualizations of arbitrary data sources. As the positive effects of uncertainty communication to all kinds of visualizations were discussed over the past years in the academic world, this work examines the uncertaintyawareness of open source solutions. Through a categorization and classification of available tools, this paper identifies the problems in uncertainty-awareness of available open source solutions. To solve this problem, a new paradigm of data handling that extends raw datasets by its uncertainty is suggested