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Articles 1 - 7 of 7
Full-Text Articles in Engineering
Convex Relaxations For Particle-Gradient Flow With Applications In Super-Resolution Single-Molecule Localization Microscopy, Hesam Mazidisharfabadi
Convex Relaxations For Particle-Gradient Flow With Applications In Super-Resolution Single-Molecule Localization Microscopy, Hesam Mazidisharfabadi
McKelvey School of Engineering Theses & Dissertations
Single-molecule localization microscopy (SMLM) techniques have become advanced bioanalytical tools by quantifying the positions and orientations of molecules in space and time at the nanoscale. With the noisy and heterogeneous nature of SMLM datasets in mind, we discuss leveraging particle-gradient flow 1) for quantifying the accuracy of localization algorithms with and without ground truth and 2) as a basis for novel, model-driven localization algorithms with empirically robust performance. Using experimental data, we demonstrate that overlapping images of molecules, a typical consequence of densely packed biological structures, cause biases in position estimates and reconstruction artifacts. To minimize such biases, we develop …
Domain Specific Computing In Tightly-Coupled Heterogeneous Systems, Anthony Michael Cabrera
Domain Specific Computing In Tightly-Coupled Heterogeneous Systems, Anthony Michael Cabrera
McKelvey School of Engineering Theses & Dissertations
Over the past several decades, researchers and programmers across many disciplines have relied on Moores law and Dennard scaling for increases in compute capability in modern processors. However, recent data suggest that the number of transistors per square inch on integrated circuits is losing pace with Moores laws projection due to the breakdown of Dennard scaling at smaller semiconductor process nodes. This has signaled the beginning of a new “golden age in computer architecture” in which the paradigm will be shifted from improving traditional processor performance for general tasks to architecting hardware that executes a class of applications in a …
Investigating Single Precision Floating General Matrix Multiply In Heterogeneous Hardware, Steven Harris
Investigating Single Precision Floating General Matrix Multiply In Heterogeneous Hardware, Steven Harris
McKelvey School of Engineering Theses & Dissertations
The fundamental operation of matrix multiplication is ubiquitous across a myriad of disciplines. Yet, the identification of new optimizations for matrix multiplication remains relevant for emerging hardware architectures and heterogeneous systems. Frameworks such as OpenCL enable computation orchestration on existing systems, and its availability using the Intel High Level Synthesis compiler allows users to architect new designs for reconfigurable hardware using C/C++. Using the HARPv2 as a vehicle for exploration, we investigate the utility of several of the most notable matrix multiplication optimizations to better understand the performance portability of OpenCL and the implications for such optimizations on this and …
Exploring Usage Of Web Resources Through A Model Of Api Learning, Finn Voichick
Exploring Usage Of Web Resources Through A Model Of Api Learning, Finn Voichick
McKelvey School of Engineering Theses & Dissertations
Application programming interfaces (APIs) are essential to modern software development, and new APIs are frequently being produced. Consequently, software developers must regularly learn new APIs, which they typically do on the job from online resources rather than in a formal educational context. The Kelleher–Ichinco COIL model, an acronym for “Collection and Organization of Information for Learning,” was recently developed to model the entire API learning process, drawing from information foraging theory, cognitive load theory, and external memory research. We ran an exploratory empirical user study in which participants performed a programming task using the React API with the goal of …
Exploring Attacks And Defenses In Additive Manufacturing Processes: Implications In Cyber-Physical Security, Nicholas Deily
Exploring Attacks And Defenses In Additive Manufacturing Processes: Implications In Cyber-Physical Security, Nicholas Deily
McKelvey School of Engineering Theses & Dissertations
Many industries are rapidly adopting additive manufacturing (AM) because of the added versatility this technology offers over traditional manufacturing techniques. But with AM, there comes a unique set of security challenges that must be addressed. In particular, the issue of part verification is critically important given the growing reliance of safety-critical systems on 3D printed parts. In this thesis, the current state of part verification technologies will be examined in the con- text of AM-specific geometric-modification attacks, and an automated tool for 3D printed part verification will be presented. This work will cover: 1) the impacts of malicious attacks on …
Predicting Disease Progression Using Deep Recurrent Neural Networks And Longitudinal Electronic Health Record Data, Seunghwan Kim
Predicting Disease Progression Using Deep Recurrent Neural Networks And Longitudinal Electronic Health Record Data, Seunghwan Kim
McKelvey School of Engineering Theses & Dissertations
Electronic Health Records (EHR) are widely adopted and used throughout healthcare systems and are able to collect and store longitudinal information data that can be used to describe patient phenotypes. From the underlying data structures used in the EHR, discrete data can be extracted and analyzed to improve patient care and outcomes via tasks such as risk stratification and prospective disease management. Temporality in EHR is innately present given the nature of these data, however, and traditional classification models are limited in this context by the cross- sectional nature of training and prediction processes. Finding temporal patterns in EHR is …
Predicting Disease Progression Using Deep Recurrent Neural Networks And Longitudinal Electronic Health Record Data, Seunghwan Kim
Predicting Disease Progression Using Deep Recurrent Neural Networks And Longitudinal Electronic Health Record Data, Seunghwan Kim
McKelvey School of Engineering Theses & Dissertations
Electronic Health Records (EHR) are widely adopted and used throughout healthcare systems and are able to collect and store longitudinal information data that can be used to describe patient phenotypes. From the underlying data structures used in the EHR, discrete data can be extracted and analyzed to improve patient care and outcomes via tasks such as risk stratification and prospective disease management. Temporality in EHR is innately present given the nature of these data, however, and traditional classification models are limited in this context by the cross-sectional nature of training and prediction processes. Finding temporal patterns in EHR is especially …