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Homocysteine Reduction For Stroke Prevention: Regarding The Recent Aha/Asa 2021 Prevention Of Stroke In Patients With Stroke And Transient Ischemic Attack, Craig Brown, Jianhua Wang, Hong Jiang, Merrill F. Elias
Homocysteine Reduction For Stroke Prevention: Regarding The Recent Aha/Asa 2021 Prevention Of Stroke In Patients With Stroke And Transient Ischemic Attack, Craig Brown, Jianhua Wang, Hong Jiang, Merrill F. Elias
Maine-Syracuse Longitudinal Papers
Reduction of secondary ischemic stroke risk following an initial stroke is an important goal. The 2021 Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack assembles opportunities for up to 80% secondary stroke reduction. Homocysteine reduction was not included in the recommendations. The reduction of homocysteine with low doses of folic acid has been shown to reduce ischemic stroke and all stroke. This has been obscured by studies using high doses of folic acid and cyanocobalamin in patients with renal failure and Methylenetetrahydrofolate reductase (MTHFR) polymorphisms. The confounding impacts of high dose folic acid and cyanocobalamin toxicity in …