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Full-Text Articles in Engineering
Microrna Gene Expression States Underlying Individual Variation In Aging And Lifespan In Isogenic C. Elegans, Holly Kinser
Microrna Gene Expression States Underlying Individual Variation In Aging And Lifespan In Isogenic C. Elegans, Holly Kinser
McKelvey School of Engineering Theses & Dissertations
Average lifespan differs greatly between species, but lifespan among same-species individuals is also highly variable. While much effort has been devoted to uncovering longevity-associated traits and lifespan-extending perturbations in humans and model organisms, how differences in lifespan arise between individuals is unknown. Studies of human identical twins demonstrate that surprisingly little of the variation in lifespan between individuals can be explained by genetics and shared environment. Furthermore, even genetically identical C. elegans reared in highly homogeneous environments display a degree of variability in lifespan similar to that of outbred human populations. Thus, longevity must be determined at least in part …
Exploring Usage Of Web Resources Through A Model Of Api Learning, Finn Voichick
Exploring Usage Of Web Resources Through A Model Of Api Learning, Finn Voichick
McKelvey School of Engineering Theses & Dissertations
Application programming interfaces (APIs) are essential to modern software development, and new APIs are frequently being produced. Consequently, software developers must regularly learn new APIs, which they typically do on the job from online resources rather than in a formal educational context. The Kelleher–Ichinco COIL model, an acronym for “Collection and Organization of Information for Learning,” was recently developed to model the entire API learning process, drawing from information foraging theory, cognitive load theory, and external memory research. We ran an exploratory empirical user study in which participants performed a programming task using the React API with the goal of …