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Full-Text Articles in Engineering

Peptoid-Functionalized Gold Nanoparticles For Zika Virus Envelope Protein Detection, Meagan Olsen May 2021

Peptoid-Functionalized Gold Nanoparticles For Zika Virus Envelope Protein Detection, Meagan Olsen

Chemical Engineering Undergraduate Honors Theses

Detection and identification of viral pathogens is essential in providing effective and rapid medical treatment. Well-established detection methods can be expensive, slow, and sometimes unable to provide the needed sensitivity and specificity. The Zika virus is one clinically relevant pathogen that cannot be easily identified due to cross-reactivity with other viruses from the same family. Electrochemical sensors enhanced with peptoid-functionalized gold nanoparticles (AuNPs) are an alternative to traditional techniques that offers rapid, accurate, label-free pathogen detection for point-of-care diagnostics. To this end, a peptoid capable of binding to the Zika virus envelope protein was developed and its binding affinity for …


Group Iv Environmentally Benign, Inexpensive Semiconductor Nanomaterials For Solar Cells, Lisa Je Jun 2019

Group Iv Environmentally Benign, Inexpensive Semiconductor Nanomaterials For Solar Cells, Lisa Je

ENGS 86 Independent Projects (AB Students)

Modern solar cells are composed of silicon, cadmium tellurium, and copper indium gallium diselenide. While these materials are efficient, elements such as cadmium and indium are rare and expensive. To make this renewable energy source more inexpensive and sustainable, the Liu Optics lab is substituting expensive rare earth metals for more commonly found transition state metals. Work has been done to replace the solar cell layers composed of cadmium and gallium to replace them with glass, silicon, and/or thin films. Common metals such as germanium and tin are investigated and characterized to provide a platform for solar cell components.


Study Of The Self-Assembly Process Of Microporous Materials Using Molecular Modeling, Mohammad Navaid Khan Nov 2016

Study Of The Self-Assembly Process Of Microporous Materials Using Molecular Modeling, Mohammad Navaid Khan

Doctoral Dissertations

Zeolites are an important class of materials in modern technology with applications in catalysis, separations, biosensing and microelectronics. There are over 200 different zeolite frameworks reported in literature, but only a handful have been used commercially. Understanding their self-assembly process would assist in the fabrication of new zeolites through the control of their pore size/shape, and surface area for advanced applications. With our research we aim to elucidate aspects of zeolite formation using molecular simulations. We have extended the lattice model of silica tetrahedra developed by Jin et al. [L. Jin, S. M. Auerbach and P. A. Monson J. Chem. …


Creation Of An Annotated Library On Fda Approved Nanomedicines, Marley R. Hodson, Tanin Izadi, Nastassja Lewinski Ph.D, Bridget T. Mcinnes Ph.D Jan 2015

Creation Of An Annotated Library On Fda Approved Nanomedicines, Marley R. Hodson, Tanin Izadi, Nastassja Lewinski Ph.D, Bridget T. Mcinnes Ph.D

Undergraduate Research Posters

Nanomedicine is a type of nanotechnology used in the medical field to limit the dosage amount and target drug delivery to specific cells. Nanomedicines that are approved and used tend to be extremely successful; however despite over a decade of research, only a limited number of nanomedicines have advanced for clinical use. A possible reason for the numerous nanomedicine failures is lack of easily accessible information and research on previous nanomedicines. In this project, we have compiled nanomedicine labeling information from the Drugs@FDA website. We have extracted phrases/sentences from labels relating to keywords on nanomaterial properties and drug profile characteristics. …


Developent Of A Phospholipid Encapsulation Process For Quantum Dots To Be Used In Biologic Applications, Logan Grimes Jun 2014

Developent Of A Phospholipid Encapsulation Process For Quantum Dots To Be Used In Biologic Applications, Logan Grimes

Master's Theses

The American Cancer Society predicts that 1,665,540 people will be diagnosed with cancer, and 585,720 people will die from cancer in 2014. One of the most common types of cancer in the United States is skin cancer. Melanoma alone is predicted to account for 10,000 of the cancer related deaths in 2014. As a highly mobile and aggressive form of cancer, melanoma is difficult to fight once it has metastasized through the body. Early detection in such varieties of cancer is critical in improving survival rates in afflicted patients. Present methods of detection rely on visual examination of suspicious regions …