Engineering Commons^™

Histological Evidence For The Therapeutic Effect Of Chitosan Nanofibrous Dressing On Acute Skin Wounds In A Rat Model, Mahboubeh Ghanbari, Sayed Ahmadreza Razian, Sara Cartwright, Yury Salkovskiy, Jason Mactaggart, Mark A. Carlson

UNO Student Research and Creative Activity Fair

Introduction: Large-area skin traumas, such as thermal burns, are among the most severe health issues that decrease patients’ quality of life and burden healthcare systems. The CDC estimates that there are 1.1 million burns requiring medical attention each year, with more than 20,000 cases involving at least 25% of the body surface, resulting in 4,500 deaths. In addition, about 10,000 people die from burn-related infections. A promising solution to alleviate this problem is using wound dressings based on biopolymers with inherent wound healing properties and biodegradability. One of these biopolymers is chitosan, which is derived from arthropod shells and exhibits …

The Effects Of Demographics And Risk Factors On The Morphological Characteristics Of Human Femoropopliteal Arteries, Sayed Ahmadreza Razian, Majid Jadidi, Alexey Kamenskiy

UNO Student Research and Creative Activity Fair

Background: Disease of the lower extremity arteries (Peripheral Arterial Disease, PAD) is associated with high morbidity and mortality. During disease development, the arteries adapt by changing their diameter, wall thickness, and residual deformations, but the effects of demographics and risk factors on this process are not clear.

Methods: Superficial femoral arteries from 736 subjects (505 male, 231 female, 12 to 99 years old, average age 51±17.8 years) and the associated demographic and risk factor variables were used to construct machine learning (ML) regression models that predicted morphological characteristics (diameter, wall thickness, and longitudinal opening angle resulting from the …

Breaks In Longitudinal Elastic Fibers Of Human Femoropopliteal Arteries, Elham Zamani

UNO Student Research and Creative Activity Fair

Breaks in Longitudinal Elastic Fibers of Human Femoropopliteal Arteries

Elham Zamani1, Majid Jadidi1

1 Department of Biomechanics, University of Nebraska Omaha, Omaha, NE

Introduction: Elastin is a major protein in the body with half-life >50 years. It is thought that elastic fibers are formed before the postnatal period. In the femoropopliteal artery (FPA), the main artery in the leg, longitudinal elastic fibers are present in External Elastic Lamina (EEL). Our team has studied more than 1000 cadaveric human FPA and has noticed that there are big breaks in their longitudinal elastic fibers in some subjects. Our goal in this work …

Mobility-Based Models For Advancing Diagnostic/Predictive Healthcare, Elham Rastegari

UNO Student Research and Creative Activity Fair

Functional ability has been always considered as one of the important determining factors of individuals’ health and quality of life. Traditional movement analysis systems require expensive facilities and frequent visits for patients to specialized laboratories. Portability and affordability of wearable sensors along with their improved accuracy and capability of monitoring movement during daily activities make them a potential alternative for analyzing mobility patterns for clinical and health assessment purposes. Wearable-based movement data, when combined with other relevant clinical or laboratory data, could enhance evidence-based healthcare and data-driven Clinical Decision Support Systems (CDSS). Utilizing the data from wearable devices, many researchers …

Acl Reconstruction Results In Alterations For Force Control Variability During Multidirectional Force Production, Amelia S. Lanier

UNO Student Research and Creative Activity Fair

After anterior cruciate ligament (ACL) rupture most will undergo reconstructive surgery. Within the first year after surgery 25% of patients will re-tear their ACL. Most of those injured attempt to return to sports which include running and cutting. The ability to produce appropriate ground reaction forces may be crucial for the successful return to sports without re-injury. Understanding stability of multidirectional ground reaction force (mGRF) production in healthy and ACL reconstructed (ACL-r) patients can lend insight to the high instance of re-injury. Typically, stability has been measured using linear analyses, but these analyses cannot capture the subtle time varying changes …