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Full-Text Articles in Engineering

Computational Modeling Of The Human Brain For Mtbi Prediction And Diagnosis, Yanir Levy Aug 2020

Computational Modeling Of The Human Brain For Mtbi Prediction And Diagnosis, Yanir Levy

Electronic Thesis and Dissertation Repository

Sports related concussions and mild traumatic brain injuries have seen an increase in frequency over the past decade. The creation of highly biofidelic computational head models is an important step in understanding the mechanisms of these mild brain injuries and preventing them. Hence, the purpose of this research is to combine state-of-the-art computational models, brain imaging modalities and traditional head injury assessment protocols to simulate and predict the brains responses during traumatic head impacts. A novel, atlas-based, parcellated axon fiber embedded head model was developed which allows for in-depth analysis of the brain’s structural connectome tracts for injury diagnosis and …


The Influence Of Heterogeneous Meninges On The Brain Mechanics Under Primary Blast Loading, Linxia Gu, Mehdi S. Chafi, Shailesh Ganpule, Namas Chandra Apr 2012

The Influence Of Heterogeneous Meninges On The Brain Mechanics Under Primary Blast Loading, Linxia Gu, Mehdi S. Chafi, Shailesh Ganpule, Namas Chandra

Department of Mechanical and Materials Engineering: Faculty Publications

In the modeling of brain mechanics subjected to primary blast waves, there is currently no consensus on how many biological components to be used in the brain–meninges–skull complex, and what type of constitutive models to be adopted. The objective of this study is to determine the role of layered meninges in damping the dynamic response of the brain under primary blast loadings. A composite structures composed of eight solid relevant layers (including the pia, cerebrospinal fluid (CSF), dura maters) with different mechanical properties are constructed to mimic the heterogeneous human head. A hyper-viscoelastic material model is developed to better represent …