Engineering Commons^™

Power Dissipation And Power Correlations For A Retreatblade Impeller Under Different Baffling Conditions, Chadakarn Sirasitthichoke

Theses

Glass-lined stirred reactors and tanks are commonly used in the pharmaceutical industry because of their corrosion resistance, ease of cleanliness and minimization of product contamination. Most industrial glass-lined tank reactors are provided with a torispherical tank bottom and a retreat curve impeller with low impeller clearance from the vessel bottom. The power, P, dissipated by the impeller is a critical process parameter to mixing processes to achieve the desired mixing effect, especially since the power per unit volume, P/V, directly controls mass transfer processes and other mixing phenomena. However, little information has been published about the power dissipation and the …

Hydrodynamic Cfd Modeling Of A Pharmaceutical Reactor Vessel Provided With A Retreat-Blade Impeller Under Different Baffling Conditions, Christopher G. Foehner

Theses

In the pharmaceutical industry, glass-lined reactors and vessels are often utilized to carry out a variety of different unit operations. Within these systems, both the vessel and impellers are typically glass-lined in order to provide superior corrosion resistance, prevent product contamination, and enhance cleanability. This approach, in turn, often requires the use of different, and sometimes sub-optimal, baffling conditions, which affect the hydrodynamics of the vessels and the reactor performance.

Computational Fluid Dynamics (CFD) is a computational tool that employs numerical methods and algorithms to discretize and numerically solve partial differential equations (PDEs) representing mass, energy, and momentum conservation equations …

Experimental Investigation Of Mixing Time In A Stirred, Torispherical-Bottomed Tank Equipped With A Retreat-Blade Impeller, Nonjaros Chomcharn

Theses

Glass-lined reactors are typically used in the pharmaceutical and specialty chemicals industries because of their material compatibility with most reactants and their cleanability. These reactors are typically equipped with a retreat-blade impeller placed close to the bottom of the tank a single baffle mounted from the top. The mixing performance of such reactors has not received significant attention in the literature, despite their ubiquitous presence in the pharmaceutical industry. In particular, mixing time, i.e., the time required by the system to achieve a predefined level of homogeneity, has not been studied to any significant degree.

In this work, the mixing …