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Full-Text Articles in Engineering

Concurrent Detection And Isolation Of Cellular And Molecular Biomarkers, Wanfeng Huang Dec 2016

Concurrent Detection And Isolation Of Cellular And Molecular Biomarkers, Wanfeng Huang

Open Access Dissertations

Detection of cancer markers such as protein biomolecules and cancer cells in bodily fluids is of great importance in early diagnosis, prognosis as well as evaluation of therapy efficacy. Numerous devices have been developed for detecting either cellular or molecular targets, however there has not yet been a system that can simultaneously detect both cellular and molecular targets effectively. Molecule and cell-based assays are important because each type of target can tell a different story about the state of the disease and the two types of information can potentially be combined and/or compared for more accurate biological or clinical assessments. …


Fundamental Studies Of Electrochemical Reactions And Microfluidics In Proton Exchange Membrane Electrolyzer Cells, Jingke Mo Dec 2016

Fundamental Studies Of Electrochemical Reactions And Microfluidics In Proton Exchange Membrane Electrolyzer Cells, Jingke Mo

Doctoral Dissertations

In electrochemical energy devices, including fuel cells, electrolyzers and batteries, the electrochemical reactions occur only on triple phase boundaries (TPBs). The boundaries provide the conductors for electros and protons, the catalysts for electrochemical reactions and the effective pathways for transport of reactants and products. The interfaces have a critical impact on the overall performance and cost of the devices in which they are incorporated, and therefore could be a key feature to optimize in order to turn a prototype into a commercially viable product. For electrolysis of water, proton exchange membrane electrolyzer cells (PEMECs) have several advantages compared to other …


Analysis Of Shock-Plugs In Quasi-One-Dimensional Compressible Flow, Matthew Alexander Thompson May 2016

Analysis Of Shock-Plugs In Quasi-One-Dimensional Compressible Flow, Matthew Alexander Thompson

Graduate Theses - Mechanical Engineering

At small length scales, such as in micro-nozzles, the assumption that a shock wave is infinitesimally thin breaks-down due to the thickness of the shock being non-negligible compared to the dimensions of the nozzle. In this thesis, shock waves of finite thickness, or “shock-plugs,” are modeled using the same methods and assumptions as a standard shock wave analysis. Due to the finite thickness of shock-plugs, however, two additional parameters are required in order to account for the differing inlet and exit areas, as well as the pressure on the side walls of the channel. A “typical” micro-nozzle with appropriate dimensions …