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Simulation And Optimization Of A Sheathless Size-Based Acoustic Particle Separator, Shivaraman Asoda
Simulation And Optimization Of A Sheathless Size-Based Acoustic Particle Separator, Shivaraman Asoda
USF Tampa Graduate Theses and Dissertations
Standing surface acoustic waves (SSAW) have been widely used for sorting of cells and particles. However, the major challenges faced with the acoustic driven separation process is the need for an optimized setup to achieve effective separation and the range of particles that can be separated. In this thesis, a custom simulation model is studied to investigate and optimize the separation of varying size particles in a sheathless acoustic separation platform that was developed in our research lab. Specifically, the effect of flowrate, pressure amplitude, wavelength and interdigitated transducers (IDTs) physical parameters on the separation efficiency is explored. We also …
An Acoustic-Based Microfluidic Platform For Active Separation And Mixing, Myeong Chan Jo
An Acoustic-Based Microfluidic Platform For Active Separation And Mixing, Myeong Chan Jo
USF Tampa Graduate Theses and Dissertations
Particle separation is of great interest to many biological and biomedical applications. Flow-based methods have been used to sort particles and cells. However, the main challenge with flow based particle separation systems is the need for a sheath flow for successful operation. Existence of the sheath liquid dilutes the analyte, necessitates precise flow control between sample and sheath flow, requires a complicated design to create sheath flow and separation efficiency depends on the sheath liquid composition. In addition, current gold standard active separation techniques are only capable of separation based on particle size; hence, separation cannot be achieved for same-size …