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Mechanical Engineering

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Mechanical Engineering Faculty Publications and Presentations

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2019

Blood clotting; Mechanical properties; Polyurethane; Thermal properties; Thrombosis

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Full-Text Articles in Engineering

Thermal And Physico-Mechanical Characterizations Of Thromboresistant Polyurethane Films, Aaron C. Wilson, Shih-Feng Chou, Roberto Lozano, Jonathan Y. Chen, Pierre F. Neuenschwander Aug 2019

Thermal And Physico-Mechanical Characterizations Of Thromboresistant Polyurethane Films, Aaron C. Wilson, Shih-Feng Chou, Roberto Lozano, Jonathan Y. Chen, Pierre F. Neuenschwander

Mechanical Engineering Faculty Publications and Presentations

Hemocompatibility remains a challenge for injectable and/or implantable medical devices, and thromboresistant coatings appear to be one of the most attractive methods to down-regulate the unwanted enzymatic reactions that promote the formation of blood clots. Among all polymeric materials, polyurethanes (PUs) are a class of biomaterials with excellent biocompatibility and bioinertness that are suitable for the use of thromboresistant coatings. In this work, we investigated the thermal and physico-mechanical behaviors of ester-based and ether-based PU films for potential uses in thromboresistant coatings. Our results show that poly(ester urethane) and poly(ether urethane) films exhibited characteristic peaks corresponding to their molecular configurations. …